| Organism name | Viguiera gardneri | 
|---|---|
| Genus | Viguiera | 
| Family | Asteraceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Viguiera gardneri | 
|---|---|
| Linked NCBI taxonomy ID | 99451 | 
| Linked level | species | 
| Family in NCBI taxonomy | Asteraceae | 
|---|---|
| ID | 4210 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00001062   | Isokaempferide / Kaempferol 3-methyl ether / 5,7,4'-trihydroxy-3-methoxyflavone | CHEMBL165064 | 19 / 4 / 3 | No. 3 | No. 15 |   | ||
| C00003885   | Nepetin / Eupafolin / 6-Methoxyluteolin | CHEMBL172350 | 31 / 34 / 60 | No. 3 | No. 15 |   | ||
| C00034885   | Prenyletin | CHEMBL607536 | 9 / 2 / 3 | No. 466 | No. 25 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001062 C00003885 C00034885 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001062 C00003885 C00034885 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001062 C00003885 C00034885 | 0 / 0 | 
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00001062 C00003885 | 2 / 1 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001062 C00003885 | 0 / 0 | 
| P06746 | DNA polymerase beta | Enzyme | C00001062 C00003885 | 0 / 0 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001062 C00003885 | 0 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001062 C00003885 | 0 / 0 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001062 C00003885 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001062 C00034885 | 0 / 1 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001062 C00003885 | 0 / 0 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00001062 C00003885 | 1 / 1 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00001062 C00003885 | 0 / 0 | 
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00003885 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00034885 | 0 / 0 | 
| P54132 | Bloom syndrome protein | Enzyme | C00003885 | 1 / 2 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003885 | 2 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003885 | 0 / 0 | 
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003885 | 3 / 1 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001062 | 0 / 0 | 
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00003885 | 0 / 0 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00003885 | 2 / 3 | 
| P04745 | Alpha-amylase 1 | Enzyme | C00003885 | 0 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00034885 | 0 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00034885 | 2 / 2 | 
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003885 | 1 / 1 | 
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00003885 | 1 / 0 | 
| P55210 | Caspase-7 | C14 | C00034885 | 0 / 0 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00003885 | 0 / 0 | 
| P29466 | Caspase-1 | C14 | C00034885 | 0 / 0 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00003885 | 1 / 1 | 
| P04062 | Glucosylceramidase | Enzyme | C00003885 | 6 / 4 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003885 | 4 / 3 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001062 | 0 / 0 | 
| Q07817 | Bcl-2-like protein 1 | Other cytosolic protein | C00001062 | 0 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00003885 | 1 / 1 | 
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00001062 | 0 / 0 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00003885 | 7 / 37 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001062 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00003885 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003885 | 1 / 2 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00003885 | 0 / 0 | 
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001062 | 1 / 0 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #210900 | Bloom syndrome; blm | P54132 | 
| #114500 | Colorectal cancer; crc | P84022 Q14191 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #133239 | Esophageal cancer | P04637 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #608013 | Gaucher disease, perinatal lethal | P04062 | 
| #230800 | Gaucher disease, type i | P04062 | 
| #230900 | Gaucher disease, type ii | P04062 | 
| #231000 | Gaucher disease, type iii | P04062 | 
| #231005 | Gaucher disease, type iiic | P04062 | 
| #232300 | Glycogen storage disease ii | P10253 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #211980 | Lung cancer | P04637 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay | P55789 | 
| #257220 | Niemann-pick disease, type c1; npc1 | O15118 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #168600 | Parkinson disease, late-onset; pd | P04062 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth | P10828 | 
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth | P10828 | 
| #145650 | Thyroid hormone resistance, selective pituitary; prth | P10828 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| #277700 | Werner syndrome; wrn | Q14191 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) P04637 (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00136 | Niemann-Pick disease type C (NPC) | O15118
                            (related) | 
| H00066 | Lewy body dementia (LBD) | P04062
                            (related) | 
| H00126 | Gaucher disease | P04062
                            (related) | 
| H00426 | Defects in the degradation of ganglioside | P04062
                            (related) | 
| H00810 | Progressive myoclonic epilepsy (PME) | P04062
                            (related) | 
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) | 
| H00018 | Gastric cancer | P04637
                            (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) P08684 (marker) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H00069 | Glycogen storage diseases (GSD) | P10253
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00249 | Thyroid hormone resistance syndrome | P10828
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H00094 | DNA repair defects | P54132
                            (related) | 
| H00296 | Defects in RecQ helicases | P54132
                            (related) Q14191 (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) | 
| H00403 | Disorders of nucleotide excision repair | Q9Y253
                            (related) |