Serratula wolfi
Species
KNApSAcK Entry
| Organism name | Serratula wolfi |
|---|---|
| Genus | Serratula |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Serratula |
|---|---|
| Linked NCBI taxonomy ID | 41634 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001062
|
Isokaempferide
/ Kaempferol 3-methyl ether / 5,7,4'-trihydroxy-3-methoxyflavone |
CHEMBL165064
|
19 / 4 / 3 | No. 3 | No. 15 |
|
||
|
C00003110
|
Caryophyllene
/ (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene |
CHEMBL445740
CHEMBL448700 |
2 / 3 / 7 | No. 478 | No. 38 |
|
||
|
C00012483
|
Betula pubescens
/ Caryophyllene oxide / trans-Caryophyllene oxide / beta-Caryophyllene epoxide / (-)-Epoxydihydrocaryophyllene / 6,7-Epoxy-3(15)-caryophyllene / (-)-beta-Caryophyllene epoxide / 4beta,5alpha-Epoxycaryophyllene / Caryophyllene 4beta,5alpha-epoxide |
CHEMBL399036
CHEMBL508894 CHEMBL479134 CHEMBL1513806 CHEMBL1553274 |
3 / 1 / 3 | No. 500 |
|
|||
|
C00030755
|
Methyl palmitate
/ Methyl hexadecanoate |
CHEMBL335125
|
C019012
|
2 / 0 / 0 | 0 / 1 | No. 793 |
|
|
|
C00030757
|
Methyl linoleate
/ Methyl 9Z,12Z-octadecadienoate |
C005575
|
No. 1785 |
|
||||
|
C00011720
|
Germacrene D
/ (-)-Germacrene D |
CHEMBL105432
CHEMBL1836650 |
No. 2639 | No. 38 |
|
Human Protein / Gene in interactions
25 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001062 C00012483 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001062 | 1 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001062 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00001062 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00012483 | 0 / 1 |
| P34972 | Cannabinoid receptor 2 | Cannabinoid receptor | C00030755 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001062 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001062 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001062 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00030755 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001062 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00012483 | 1 / 1 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00001062 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001062 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001062 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001062 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001062 | 0 / 0 |
| Q07817 | Bcl-2-like protein 1 | Other cytosolic protein | C00001062 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001062 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001062 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001062 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001062 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00003110 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003110 | 1 / 2 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00001062 | 2 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (8)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (12)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|