Nothofagus antarctica
Species
KNApSAcK Entry
| Organism name | Nothofagus antarctica |
|---|---|
| Genus | Nothofagus |
| Family | Nothofagaceae / Fagaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Nothofagus antarctica |
|---|---|
| Linked NCBI taxonomy ID | 28933 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Nothofagaceae |
|---|---|
| ID | 26778 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001071
|
Myricetin
|
CHEMBL164
|
C040015
|
78 / 70 / 56 | 39 / 2 | No. 3 | No. 15 |
|
|
C00004554
|
3-Hydroxywogonin
/ 8-Methoxygalangin / 8-Hydroxygalangin 8-methyl ether / 3,5,7-Trihydroxy-8-methoxyflavone / 3,5,7-Trihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00004536
|
Izalpinin
/ 7-O-Methylgalangin / Galangin 7-methyl ether / 3,5-Dihydroxy-7-methoxyflavone / 3,5-Dihydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one |
CHEMBL464966
|
No. 3 | No. 15 |
|
|||
|
C00004533
|
Galangin
/ Norizalpinin / 3,5,7-Trihydroxyflavone / 3,5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one |
CHEMBL309490
|
C037032
|
35 / 34 / 29 | 15 / 4 | No. 76 | No. 15 |
|
|
C00007233
|
Isosalipurpol
/ Chalconaringenin / Naringenin chalcone / trans-2',4,4',6'-Tetrahydroxychalcone / (2E)- 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-Propen-1-one |
CHEMBL338066
|
12 / 20 / 21 | No. 92 | No. 13 |
|
Human Protein / Gene in interactions
96 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001071 C00004533 C00007233 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001071 C00004533 C00007233 | 1 / 2 |
| O00255 | Menin | Unclassified protein | C00001071 C00004533 C00007233 | 2 / 5 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001071 C00004533 C00007233 | 4 / 3 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001071 C00004533 C00007233 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001071 C00004533 C00007233 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001071 C00004533 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001071 C00004533 | 1 / 1 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00001071 C00004533 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00001071 C00004533 | 1 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00001071 C00007233 | 0 / 3 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001071 C00007233 | 0 / 0 |
| P06276 | Cholinesterase | Hydrolase | C00001071 C00004533 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00001071 C00007233 | 6 / 4 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001071 C00004533 | 4 / 4 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00001071 C00004533 | 2 / 2 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001071 C00004533 | 1 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00001071 C00004533 | 1 / 1 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00001071 C00004533 | 1 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001071 C00007233 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001071 C00004533 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00001071 C00004533 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001071 C00004533 | 0 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001071 | 0 / 0 |
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00001071 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001071 | 1 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00001071 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00004533 | 1 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00001071 | 2 / 3 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00004533 | 0 / 0 |
| Q15746 | Myosin light chain kinase, smooth muscle | Mlck | C00001071 | 1 / 1 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00001071 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00001071 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001071 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00001071 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001071 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001071 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00004533 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00004533 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00004533 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00004533 | 4 / 2 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00004533 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00001071 | 0 / 0 |
| Q14790 | Caspase-8 | C14 | C00001071 | 2 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00007233 | 7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001071 | 1 / 1 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00001071 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00001071 | 3 / 1 |
| P54132 | Bloom syndrome protein | Enzyme | C00001071 | 1 / 2 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00001071 | 0 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001071 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00001071 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001071 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00004533 | 0 / 1 |
| P06213 | Insulin receptor | TK tyrosine-protein kinase INSR subfamily | C00001071 | 5 / 4 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001071 | 0 / 0 |
| P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Enzyme | C00001071 | 9 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00001071 | 0 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | C00001071 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00001071 | 2 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00001071 | 0 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00004533 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001071 | 3 / 3 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00001071 | 1 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001071 | 2 / 2 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00001071 | 5 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00004533 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001071 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001071 | 2 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001071 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001071 | 1 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001071 | 0 / 0 |
| P31941 | DNA dC->dU-editing enzyme APOBEC-3A | Enzyme | C00001071 | 0 / 0 |
| Q15046 | Lysine--tRNA ligase | Enzyme | C00001071 | 2 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001071 | 0 / 0 |
| O75795 | UDP-glucuronosyltransferase 2B17 | Enzyme | C00004533 | 1 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00004533 | 5 / 1 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00004533 | 3 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00001071 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00004533 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00004533 | 3 / 4 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00004533 | 0 / 1 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00001071 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001071 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001071 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001071 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00001071 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001071 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001071 | 1 / 1 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00001071 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001071 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001071 | 1 / 4 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00007233 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001071 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00001071 | 2 / 1 |
| Q9HCT0 | Fibroblast growth factor 22 | Unclassified protein | C00001071 | 0 / 0 |
50 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00001071
C00004533
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001071
C00004533
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00001071
C00004533
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001071
C00004533
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00001071
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00004533
|
| 2034 | EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 | endothelial PAS domain protein 1 |
C00004533
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00004533
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00004533
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00004533
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00004533
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00004533
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00004533
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00004533
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00004533
|
| 1244 | ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
C00001071
|
| 397 | ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 | Rho GDP dissociation inhibitor (GDI) beta |
C00001071
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001071
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001071
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001071
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00001071
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00001071
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00001071
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001071
|
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00001071
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00004533
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00001071
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00001071
|
| 1786 | DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT | DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) |
C00001071
|
| 54583 | EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6 | egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29) |
C00001071
|
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00001071
|
| 3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | hepatocyte growth factor (hepapoietin A; scatter factor) |
C00001071
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00001071
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00001071
|
| 4233 | MET, AUTS9, HGFR, RCCP2, c-Met | met proto-oncogene (EC:2.7.10.1) |
C00001071
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00001071
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00001071
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00001071
|
| 8505 | PARG, PARG99 | poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) |
C00001071
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00001071
|
| 8000 | PSCA, PRO232 | prostate stem cell antigen |
C00001071
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00001071
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001071
|
| 23411 | SIRT1, SIR2L1 | sirtuin 1 |
C00001071
|
| 6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00001071
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00001071
|
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00001071
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00001071
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00001071
|
| 7161 | TP73, P73 | tumor protein p73 |
C00001071
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (90)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #613780 | Aortic aneurysm, familial thoracic 7; aat7 |
Q15746
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #612560 | Bone mineral density quantitative trait locus 12; bmnd12 |
O75795
|
| #114480 | Breast cancer |
P38398
P42336 |
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #607271 | Caspase 8 deficiency |
Q14790
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #613641 | Charcot-marie-tooth disease, recessive intermediate b; cmtrib |
Q15046
|
| #114500 | Colorectal cancer; crc |
P18054
P42336 P84022 Q14191 |
| #612918 | Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi |
P42336
|
| #615108 | Cowden syndrome 5; cws5 |
P42336
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #613916 | Deafness, autosomal recessive 89; dfnb89 |
Q15046
|
| #610549 | Diabetes mellitus, insulin-resistant, with acanthosis nigricans |
P06213
|
| #125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P06213
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #246200 | Donohue syndrome |
P06213
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #133239 | Esophageal cancer |
P18054
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #114550 | Hepatocellular carcinoma |
P42336
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #609968 | Hyperinsulinemic hypoglycemia, familial, 5; hhf5 |
P06213
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #182000 | Keratosis, seborrheic |
P42336
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
Q14790
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #602501 | Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap |
P42336
|
| #603387 | Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph |
P42336
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #167000 | Ovarian cancer |
P38398
P42336 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #262190 | Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities |
P06213
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (65)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00719 | Leprechaunism |
P06213
(related)
|
| H00942 | Rabson-Mendenhall syndrome |
P06213
(related)
|
| H01228 | Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) |
P06213
(related)
|
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
P06213
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P28907
(marker)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00027 | Ovarian cancer |
P38398
(related)
P42336 (related) |
| H00031 | Breast cancer |
P38398
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
Q01453
(related)
Q15046 (related) |
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00108 | Autoimmune lymphoproliferative syndromes (ALPS) |
Q14790
(related)
|
| H00801 | Familial thoracic aortic aneurysm and dissection (TAAD) |
Q15746
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|