Organism name | Cyathea spp. |
---|---|
Genus | Cyathea |
Family | Cyatheaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Cyathea |
---|---|
Linked NCBI taxonomy ID | 13470 |
Linked level | genus |
Family in NCBI taxonomy | Cyatheaceae |
---|---|
ID | 29635 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | Euphyllophyta |
---|---|
ID | 78536 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00005165
![]() |
Sophoraflavonoloside
/ Kaempferol 3-O-sophoroside / Kaempferol 3-O-beta-sophoroside |
CHEMBL500233
CHEMBL1375795 CHEMBL2032411 |
C064309
|
12 / 2 / 2 | 6 / 4 | No. 1 | No. 15 |
![]() |
C00001110
![]() |
Vitexin
/ Apigenin 8-C-glucoside / 8-D-Glucosyl-4',5,7-trihydroxyflavone / 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL487417
CHEMBL1332209 CHEMBL1357921 |
16 / 4 / 8 | No. 22 | No. 15 |
![]() |
||
C00001078
![]() |
Lutexin
/ Orientin / Luteolin 8-C-beta-D-glucopyranoside / 8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone |
CHEMBL520866
CHEMBL1468796 |
C065886
|
20 / 15 / 14 | No. 22 | No. 15 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001078 C00001110 C00005165 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00001078 C00001110 C00005165 | 1 / 1 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00001078 C00001110 C00005165 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001078 C00001110 C00005165 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00001078 C00001110 C00005165 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00001078 C00005165 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00001078 C00005165 | 1 / 1 |
Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001078 C00001110 | 0 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001078 C00005165 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00001110 C00005165 | 0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001110 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00005165 | 0 / 0 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00001078 | 0 / 0 |
P15121 | Aldose reductase | Enzyme | C00001110 | 0 / 0 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001078 | 1 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001110 | 0 / 1 |
P39748 | Flap endonuclease 1 | Enzyme | C00005165 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001110 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001110 | 0 / 1 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00001078 | 3 / 1 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00001078 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001110 | 1 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00001078 | 4 / 3 |
Q99700 | Ataxin-2 | Unclassified protein | C00001078 | 1 / 1 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001078 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00005165 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001078 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001078 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00001078 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001078 | 1 / 2 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001110 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001110 | 1 / 4 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001110 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
3146 | HMGB1, HMG1, HMG3, SBP-1 | high mobility group box 1 |
C00005165
|
3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00005165
|
6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00005165
|
7097 | TLR2, CD282, TIL4 | toll-like receptor 2 |
C00005165
|
7099 | TLR4, ARMD10, CD284, TLR-4, TOLL | toll-like receptor 4 |
C00005165
|
7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00005165
|
OMIM | preferred title | UniProt |
---|---|---|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|