| Organism name | Achillea spp. |
|---|---|
| Genus | Achillea |
| Family | Asteraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Achillea |
|---|---|
| Linked NCBI taxonomy ID | 13328 |
| Linked level | genus |
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00004684
|
Axillarin
/ Quercetagetin 3,6-dimethyl ether / 3,6-Dimethoxy-5,7,3',4'-tetrahydroxyflavone / 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3,6-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL487810
|
C056669
|
1 / 1 / 1 | No. 3 | No. 15 |
|
|
|
C00001102
|
Leucanthoside
/ Swertiajaponin / 6-beta-D-glucopyranosyl-3',4',5-trihydroxy-7-methoxyflavone |
No. 22 | No. 15 |
|
||||
|
C00006125
|
Swertisin
/ Flavocommelitin / 7-O-Methylapigenin 6-C-beta-D-glucopyranoside / 6-beta-D-Glucopyranosyl-4',5-dihydroxy-7-methoxyflavone / 6-beta-D-Glucopyranosyl-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL174243
CHEMBL486415 |
No. 22 | No. 15 |
|
|||
|
C00003248
|
Leucodin
/ Desacetoxymatricarin |
CHEMBL517040
CHEMBL1322934 CHEMBL1741501 |
C476809
|
12 / 7 / 10 | No. 298 | No. 38 |
|
|
|
C00003321
|
Matricin
|
CHEMBL497441
|
C039959
|
No. 1147 | No. 38 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003248 | 1 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00004684 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003248 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003248 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003248 | 2 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003248 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003248 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003248 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003248 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00003248 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003248 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00003248 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003248 | 1 / 2 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #278300 | Xanthinuria, type i |
P47989
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|