| Organism name | Achillea spp. | 
|---|---|
| Genus | Achillea | 
| Family | Asteraceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Achillea | 
|---|---|
| Linked NCBI taxonomy ID | 13328 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Asteraceae | 
|---|---|
| ID | 4210 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00004684   | Axillarin / Quercetagetin 3,6-dimethyl ether / 3,6-Dimethoxy-5,7,3',4'-tetrahydroxyflavone / 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3,6-dimethoxy-4H-1-benzopyran-4-one | CHEMBL487810 | C056669 | 1 / 1 / 1 | No. 3 | No. 15 |   | |
| C00001102   | Leucanthoside / Swertiajaponin / 6-beta-D-glucopyranosyl-3',4',5-trihydroxy-7-methoxyflavone | No. 22 | No. 15 |   | ||||
| C00006125   | Swertisin / Flavocommelitin / 7-O-Methylapigenin 6-C-beta-D-glucopyranoside / 6-beta-D-Glucopyranosyl-4',5-dihydroxy-7-methoxyflavone / 6-beta-D-Glucopyranosyl-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one | CHEMBL174243 CHEMBL486415 | No. 22 | No. 15 |   | |||
| C00003248   | Leucodin / Desacetoxymatricarin | CHEMBL517040 CHEMBL1322934 CHEMBL1741501 | C476809 | 12 / 7 / 10 | No. 298 | No. 38 |   | |
| C00003321   | Matricin | CHEMBL497441 | C039959 | No. 1147 | No. 38 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003248 | 1 / 0 | 
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00004684 | 1 / 1 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003248 | 0 / 1 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003248 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003248 | 2 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003248 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003248 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003248 | 1 / 1 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003248 | 0 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00003248 | 0 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003248 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00003248 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003248 | 1 / 2 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #114500 | Colorectal cancer; crc | P84022 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #278300 | Xanthinuria, type i | P47989 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00192 | Xanthinuria | P47989
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) |