Aspergillus niger

• Index
• Plant Species
• Metabolite list (20)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Aspergillus niger
Genus	Aspergillus
Family	Trichocomaceae
Kingdom	Fungi

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Aspergillus niger
Linked NCBI taxonomy ID	5061
Linked level	species

Family

Family in NCBI taxonomy	Aspergillaceae
ID	1131492

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Fungi
ID	4751

Plant class

Plant class
ID

Metabolite list (20)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001105	Tangeretin / 4',5,6,7,8-Pentamethoxyflavone	CHEMBL73930	C059006	12 / 11 / 11	2 / 0	No. 8	No. 15
C00048618	Asperiamide B / (-)-Asperiamide B					No. 80
C00048619	Asperiamide C / (-)-Asperiamide C					No. 80
C00003652	Ergosterol / Ergosta-5,7,22-trien-3beta-ol	CHEMBL222608 CHEMBL1232562 CHEMBL1512075 CHEMBL1741735 CHEMBL1965225	D004875	12 / 14 / 11		No. 111	No. 11
C00043445	Demethylkotanin	CHEMBL518901				No. 1364
C00026564	Asperazine / (+)-Asperazine					No. 2371
C00046813	Malformin C	CHEMBL599936				No. 4228
C00043856	Pyranonigrin B	CHEMBL463362				No. 4276
C00043858	Pyranonigrin D					No. 4276
C00043857	Pyranonigrin C	CHEMBL512228				No. 4276
C00035912	Cycloleucomelone					No. 4387
C00043299	Aspernigrin A					No. 4536
C00046766	Hexylitaconic acid	CHEMBL199341		1 / 1 / 5		No. 4730
C00023603	Tubingensin A					No. 5200
C00001121	beta-D-Glucosamine / 2-Amino-2-deoxy-beta-D-glucopyranose	CHEMBL234432 CHEMBL493287 CHEMBL606759		6 / 8 / 8		No. 5355
C00046868	Pyrophen	CHEMBL1334926 CHEMBL1983219	C067225	15 / 11 / 13		No. 5804
C00015490	Penitricin D					No. 7383
C00046627	Asperic acid / (+)-Asperic acid					No. 7429
C00001186	Glyoxylic acid	CHEMBL1162545	C031150	1 / 0 / 0	0 / 1	No. 7855
C00043300	Aspernigrin B					No. 8064

Human Protein / Gene in interactions

39 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10828	Thyroid hormone receptor beta	NR1A2	C00001105 C00001121	3 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001105 C00046868	1 / 2
O00255	Menin	Unclassified protein	C00001105 C00046868	2 / 5
P10636	Microtubule-associated protein tau	Unclassified protein	C00003652 C00046868	4 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001105 C00003652	0 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001105 C00003652	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00001105 C00003652	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00001121 C00003652	2 / 3
Q00987	E3 ubiquitin-protein ligase Mdm2	Other nuclear protein	C00046766	1 / 5
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003652	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003652	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00001105	1 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00046868	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00046868	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001105	0 / 0
O15245	Solute carrier family 22 member 1	Drug uniporter	C00001121	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00001121	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003652	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00001121	1 / 3
P08183	Multidrug resistance protein 1	drug	C00001105	1 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00001105	2 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003652	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003652	1 / 1
P14780	Matrix metalloproteinase-9	M10A	C00001121	2 / 2
Q9UNA4	DNA polymerase iota	Enzyme	C00046868	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00046868	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00046868	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00003652	5 / 1
P06746	DNA polymerase beta	Enzyme	C00046868	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00046868	0 / 0
P31939	Bifunctional purine biosynthesis protein PURH	Enzyme	C00003652	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00046868	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00046868	1 / 1
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00001105	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00046868	0 / 0
O15427	Monocarboxylate transporter 4	Unclassified protein	C00001186	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00046868	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00046868	2 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001105	1 / 1

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001105
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001105

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions