Species

KNApSAcK Entry

Organism name Lychnis dioica
Genus Lychnis
Family Caryophyllaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lychnis
Linked NCBI taxonomy ID 265240
Linked level genus

Family

Family in NCBI taxonomy Caryophyllaceae
ID 3568

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001139 External link 512 Lychnose
No. 1212
C00002665 External link 512 Phloroglucinol
CHEMBL473159
D010696
3 / 4 / 2 8 / 2 No. 1590 No. 82

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P14679 Tyrosinase Oxidoreductase C00002665 4 / 2
P56817 Beta-secretase 1 A1A C00002665 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00002665 0 / 0

8 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002665
581 BAX, BCL2L4 BCL2-associated X protein C00002665
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00002665
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00002665
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00002665
9518 GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB growth differentiation factor 15 C00002665
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00002665
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00002665

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679

KEGG DISEASE (2)

KEGG name UniProt
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D011832 Radiation Injuries C00002665
D013959 Thyroid Diseases C00002665