| Organism name | Cinnamosma fragrans | 
|---|---|
| Genus | Cinnamosma | 
| Family | Canellaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Cinnamosma | 
|---|---|
| Linked NCBI taxonomy ID | 132964 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Canellaceae | 
|---|---|
| ID | 3424 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | Magnoliophyta | 
|---|---|
| ID | 3398 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00035077   | delta-Tocotrienol | CHEMBL121305 | C082097 | 1 / 0 / 0 | 10 / 0 | No. 328 |   | |
| C00020297   | Fragrolide | No. 546 | No. 38 |   | ||||
| C00003236   | Confertifolin | CHEMBL1993066 | No. 546 | No. 38 |   | |||
| C00001165   | Mannitol / D-Mannitol | CHEMBL16105 CHEMBL689 CHEMBL1682 CHEMBL1735282 CHEMBL1773904 | D008353 | 101 / 49 / 42 | 10 / 42 | No. 630 |   | |
| C00020289   | Cinnamolide | CHEMBL218666 | 1 / 0 / 0 | No. 950 | No. 38 |   | ||
| C00020293   | Bemarivolide | No. 1433 |   | |||||
| C00003117   | Cinnamodial | CHEMBL373458 CHEMBL1988492 | 1 / 0 / 0 | No. 3151 | No. 38 |   | ||
| C00041440   | Cinnafragrin B / (-)-Cinnafragrin B | CHEMBL385716 | 1 / 0 / 0 | No. 3285 |   | |||
| C00041439   | Cinnafragrin A / (-)-Cinnafragrin A | CHEMBL376261 CHEMBL218039 | 1 / 0 / 0 | No. 3285 |   | |||
| C00020299   | Bemadienolide | CHEMBL385842 | 1 / 0 / 0 | No. 5323 |   | |||
| C00041441   | Cinnafragrin C / (-)-Cinnafragrin C | CHEMBL218539 | 1 / 0 / 0 | No. 8787 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| O43451 | Maltase-glucoamylase, intestinal | Hydrolase | C00003117 C00020289 C00020299 C00035077 C00041439 C00041440 C00041441 | 0 / 0 | 
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00001165 | 2 / 1 | 
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001165 | 0 / 0 | 
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00001165 | 0 / 0 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00001165 | 0 / 3 | 
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001165 | 2 / 2 | 
| P08246 | Neutrophil elastase | S1A | C00001165 | 2 / 1 | 
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001165 | 0 / 0 | 
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00001165 | 0 / 0 | 
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00001165 | 0 / 0 | 
| P29466 | Caspase-1 | C14 | C00001165 | 0 / 0 | 
| P17252 | Protein kinase C alpha type | Alpha | C00001165 | 0 / 0 | 
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00001165 | 0 / 0 | 
| P14780 | Matrix metalloproteinase-9 | M10A | C00001165 | 2 / 2 | 
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00001165 | 0 / 0 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00001165 | 11 / 10 | 
| P00918 | Carbonic anhydrase 2 | Lyase | C00001165 | 1 / 2 | 
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00001165 | 0 / 1 | 
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00001165 | 1 / 1 | 
| P25021 | Histamine H2 receptor | Histamine receptor | C00001165 | 0 / 0 | 
| P35367 | Histamine H1 receptor | Histamine receptor | C00001165 | 0 / 0 | 
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00001165 | 1 / 0 | 
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00001165 | 0 / 0 | 
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00001165 | 0 / 0 | 
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00001165 | 0 / 0 | 
| P08183 | Multidrug resistance protein 1 | drug | C00001165 | 1 / 0 | 
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00001165 | 0 / 0 | 
| P06241 | Tyrosine-protein kinase Fyn | Src | C00001165 | 0 / 0 | 
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00001165 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001165 | 0 / 1 | 
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00001165 | 1 / 8 | 
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00001165 | 2 / 0 | 
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00001165 | 0 / 0 | 
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00001165 | 0 / 0 | 
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00001165 | 0 / 0 | 
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00001165 | 0 / 0 | 
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00001165 | 0 / 0 | 
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00001165 | 0 / 0 | 
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00001165 | 1 / 1 | 
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00001165 | 0 / 0 | 
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00001165 | 1 / 0 | 
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00001165 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00001165 | 0 / 0 | 
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001165 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00001165 | 0 / 0 | 
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00001165 | 0 / 0 | 
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00001165 | 0 / 0 | 
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00001165 | 0 / 0 | 
| P30988 | Calcitonin receptor | Calcitonin receptor | C00001165 | 0 / 0 | 
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00001165 | 1 / 0 | 
| P41143 | Delta-type opioid receptor | Opioid receptor | C00001165 | 0 / 0 | 
| Q92731 | Estrogen receptor beta | NR3A2 | C00001165 | 0 / 1 | 
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00001165 | 0 / 0 | 
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00001165 | 0 / 0 | 
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00001165 | 0 / 0 | 
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00001165 | 1 / 0 | 
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00001165 | 0 / 0 | 
| P08311 | Cathepsin G | S1A | C00001165 | 0 / 0 | 
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00001165 | 1 / 0 | 
| P03956 | Interstitial collagenase | M10A | C00001165 | 0 / 1 | 
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00001165 | 0 / 0 | 
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001165 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001165 | 0 / 0 | 
| P04150 | Glucocorticoid receptor | NR3C1 | C00001165 | 0 / 1 | 
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00001165 | 2 / 0 | 
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00001165 | 0 / 0 | 
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00001165 | 0 / 0 | 
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00001165 | 2 / 0 | 
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00001165 | 5 / 9 | 
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00001165 | 1 / 0 | 
| P21452 | Substance-K receptor | Neurokinin receptor | C00001165 | 0 / 0 | 
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00001165 | 0 / 0 | 
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00001165 | 3 / 0 | 
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00001165 | 0 / 0 | 
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00001165 | 1 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001165 | 0 / 0 | 
| P10323 | Acrosin | S1A | C00001165 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001165 | 0 / 0 | 
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00001165 | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | C00001165 | 1 / 1 | 
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00001165 | 1 / 0 | 
| P22303 | Acetylcholinesterase | Hydrolase | C00001165 | 1 / 0 | 
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00001165 | 0 / 0 | 
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00001165 | 0 / 0 | 
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001165 | 0 / 0 | 
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00001165 | 0 / 0 | 
| P25103 | Substance-P receptor | Neurokinin receptor | C00001165 | 0 / 0 | 
| P25105 | Platelet-activating factor receptor | PAF receptor | C00001165 | 0 / 0 | 
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00001165 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001165 | 1 / 1 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001165 | 0 / 1 | 
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00001165 | 0 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001165 | 0 / 0 | 
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001165 | 1 / 0 | 
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00001165 | 1 / 1 | 
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00001165 | 0 / 0 | 
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00001165 | 0 / 0 | 
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00001165 | 0 / 0 | 
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00001165 | 1 / 1 | 
| P06239 | Tyrosine-protein kinase Lck | Src | C00001165 | 0 / 1 | 
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00001165 | 0 / 0 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001165 | 1 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) | C00035077 | 
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 | C00035077 | 
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa | C00035077 | 
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | C00035077 | 
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene | C00035077 | 
| 4316 | MMP7, MMP-7, MPSL1, PUMP-1 | matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) | C00035077 | 
| 9611 | NCOR1, N-CoR, N-CoR1, TRAC1, hN-CoR | nuclear receptor corepressor 1 | C00035077 | 
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 | C00035077 | 
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | C00035077 | 
| 7471 | WNT1, BMND16, INT1, OI15 | wingless-type MMTV integration site family, member 1 | C00035077 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00001165 | 
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | C00001165 | 
| 3479 | IGF1, IGF-I, IGF1A, IGFI | insulin-like growth factor 1 (somatomedin C) | C00001165 | 
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) | C00001165 | 
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) | C00001165 | 
| 4878 | NPPA, ANF, ANP, ATFB6, CDD-ANF, PND | natriuretic peptide A | C00001165 | 
| 27250 | PDCD4, H731 | programmed cell death 4 (neoplastic transformation inhibitor) | C00001165 | 
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) | C00001165 | 
| 7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) | C00001165 | 
| 7163 | TPD52, D52, N8L, PC-1, PrLZ, hD52 | tumor protein D52 | C00001165 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism | P20309 | 
| #103780 | Alcohol dependence | P08172 P14416 P31645 | 
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | Q13148 | 
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 | Q99720 | 
| #602025 | Body mass index quantitative trait locus 9; bmiq9 | P41968 | 
| #300615 | Brunner syndrome | P21397 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #162800 | Cyclic neutropenia | P08246 | 
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 | P51681 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #613659 | Gastric cancer | P04626 | 
| #137215 | Gastric cancer, hereditary diffuse; hdgc | P04626 | 
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd | P24557 | 
| #137800 | Glioma susceptibility 1; glm1 | P04626 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #609423 | Human immunodeficiency virus type 1, susceptibility to | P41597 P51681 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #612244 | Inflammatory bowel disease 13; ibd13 | P08183 | 
| #603932 | Intervertebral disc disease; idd | P14780 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #613688 | Long qt syndrome 2; lqt2 | Q12809 | 
| #211980 | Lung cancer | P00533 P04626 | 
| #608516 | Major depressive disorder; mdd | P08172 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| %300852 | Mental retardation, x-linked 88; mrx88 | P50052 | 
| #613073 | Metaphyseal anadysplasia 2; mandp2 | P14780 | 
| #126200 | Multiple sclerosis, susceptibility to; ms | P08575 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #159900 | Myoclonic dystonia | P14416 | 
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 | P08246 | 
| #601665 | Obesity | P32245 | 
| #164230 | Obsessive-compulsive disorder; ocd | P31645 | 
| #604715 | Orthostatic intolerance | P23975 | 
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 | P00918 | 
| #167000 | Ovarian cancer | P04626 | 
| #613135 | Parkinsonism-dystonia, infantile; pkdys | Q01959 | 
| #607276 | Resting heart rate, variation in | P08588 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive | P08575 | 
| #609620 | Short qt syndrome 1; sqt1 | Q12809 | 
| #190300 | Tremor, hereditary essential, 1; etm1 | P35462 | 
| #610379 | West nile virus, susceptibility to | P51681 | 
| #112100 | Yt blood group antigen | P22303 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00016 | Oral cancer | P00533
                            (related) P00533 (marker) | 
| H00017 | Esophageal cancer | P00533
                            (related) P35354 (related) | 
| H00018 | Gastric cancer | P00533
                            (related) P04626 (related) | 
| H00022 | Bladder cancer | P00533
                            (related) P04626 (related) | 
| H00028 | Choriocarcinoma | P00533
                            (related) P03956 (related) P04626 (related) | 
| H00030 | Cervical cancer | P00533
                            (related) P04626 (related) | 
| H00042 | Glioma | P00533
                            (related) P00533 (marker) | 
| H00055 | Laryngeal cancer | P00533
                            (related) P00533 (marker) | 
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) | P00918
                            (related) | 
| H00436 | Osteopetrosis | P00918
                            (related) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00026 | Endometrial Cancer | P03372
                            (marker) P04626 (related) Q92731 (marker) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P04150
                            (related) | 
| H00019 | Pancreatic cancer | P04626
                            (related) | 
| H00027 | Ovarian cancer | P04626
                            (related) | 
| H00031 | Breast cancer | P04626
                            (related) P04626 (marker) | 
| H00046 | Cholangiocarcinoma | P04626
                            (related) P35354 (related) | 
| H00093 | Combined immunodeficiencies (CIDs) | P06239
                            (related) | 
| H00079 | Asthma | P07550
                            (related) | 
| H00100 | Neutropenic disorders | P08246
                            (related) | 
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) | P08575
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00025 | Penile cancer | P14780
                            (related) P35354 (related) | 
| H00479 | Metaphyseal dysplasias | P14780
                            (related) | 
| H00548 | Brunner syndrome | P21397
                            (related) | 
| H01031 | Orthostatic intolerance (OI) | P23975
                            (related) | 
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) | P24557
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00480 | Non-syndromic X-linked mental retardation | P50052
                            (related) | 
| H00720 | Long QT syndrome | Q12809
                            (related) | 
| H00725 | Short QT syndrome | Q12809
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | Q13148
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D058186 | Acute Kidney Injury | C00001165 | 
| D055371 | Acute Lung Injury | C00001165 | 
| D053099 | Azotemia | C00001165 | 
| D001929 | Brain Edema | C00001165 | 
| D002545 | Brain Ischemia | C00001165 | 
| D002543 | Cerebral Hemorrhage | C00001165 | 
| D003128 | COMA | C00001165 | 
| D003161 | Compartment Syndromes | C00001165 | 
| D006259 | Craniocerebral Trauma | C00001165 | 
| D003875 | Drug Eruptions | C00001165 | 
| D064420 | Drug-Related Side Effects and Adverse Reactions | C00001165 | 
| D004487 | Edema | C00001165 | 
| D004660 | Encephalitis | C00001165 | 
| D005901 | Glaucoma | C00001165 | 
| D015812 | Glaucoma, Angle-Closure | C00001165 | 
| D005910 | Glioma | C00001165 | 
| D034381 | Hearing Loss | C00001165 | 
| D006331 | Heart Diseases | C00001165 | 
| D006505 | Hepatitis | C00001165 | 
| D006955 | Hypernatremia | C00001165 | 
| D007008 | Hypokalemia | C00001165 | 
| D007010 | Hyponatremia | C00001165 | 
| D007022 | Hypotension | C00001165 | 
| D007177 | Inappropriate ADH Syndrome | C00001165 | 
| D019586 | Intracranial Hypertension | C00001165 | 
| D002546 | Ischemic Attack, Transient | C00001165 | 
| D007674 | Kidney Diseases | C00001165 | 
| D008579 | Meningioma | C00001165 | 
| D017202 | Myocardial Ischemia | C00001165 | 
| D009336 | Necrosis | C00001165 | 
| D009401 | Nephrosis | C00001165 | 
| D009422 | Nervous System Diseases | C00001165 | 
| D009846 | Oliguria | C00001165 | 
| D054038 | Posterior Leukoencephalopathy Syndrome | C00001165 | 
| D011654 | Pulmonary Edema | C00001165 | 
| D011655 | Pulmonary Embolism | C00001165 | 
| D051437 | Renal Insufficiency | C00001165 | 
| D015427 | Reperfusion Injury | C00001165 | 
| D012769 | Shock | C00001165 | 
| D020521 | Stroke | C00001165 | 
| D014581 | Urticaria | C00001165 | 
| D014693 | Ventricular Fibrillation | C00001165 |