Organism name | Sargassum crassifolium J.Asgardh |
---|---|
Genus | Sargassum |
Family | Sargassaceae |
Kingdom | Chromalveolata |
Linked NCBI taxonomy name | Sargassum |
---|---|
Linked NCBI taxonomy ID | 3015 |
Linked level | genus |
Family in NCBI taxonomy | Sargassaceae |
---|---|
ID | 3014 |
Kingdom (Superkingdom) in NCBI taxonomy | Eukaryota |
---|---|
ID | 2759 |
Plant class | |
---|---|
ID |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00001233
![]() |
Palmitic acid
|
CHEMBL82293
|
D019308
|
16 / 8 / 8 | 35 / 1 | No. 184 | No. 68 |
![]() |
C00019144
![]() |
Loliolide
/ (-)-Loliolide |
CHEMBL227113
CHEMBL446471 |
C030425
|
1 / 2 / 2 | No. 2667 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00001233 C00019144 | 2 / 2 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001233 | 0 / 0 |
P05413 | Fatty acid-binding protein, heart | Other cytosolic protein | C00001233 | 0 / 0 |
P08047 | Transcription factor Sp1 | Unclassified protein | C00001233 | 0 / 0 |
P08183 | Multidrug resistance protein 1 | drug | C00001233 | 1 / 0 |
P11387 | DNA topoisomerase 1 | Isomerase | C00001233 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00001233 | 0 / 0 |
P12104 | Fatty acid-binding protein, intestinal | Other cytosolic protein | C00001233 | 0 / 0 |
P15090 | Fatty acid-binding protein, adipocyte | Other cytosolic protein | C00001233 | 0 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | C00001233 | 0 / 1 |
O60603 | Toll-like receptor 2 | Membrane receptor | C00001233 | 1 / 1 |
Q96RI1 | Bile acid receptor | NR1H4 | C00001233 | 0 / 0 |
Q01469 | Fatty acid-binding protein, epidermal | Other cytosolic protein | C00001233 | 0 / 0 |
P03372 | Estrogen receptor | NR3A1 | C00001233 | 1 / 1 |
P10275 | Androgen receptor | NR3C4 | C00001233 | 3 / 4 |
Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00001233 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
9619 | ABCG1, ABC8, WHITE1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
C00001233
|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00001233
|
213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00001233
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001233
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001233
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001233
|
840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00001233
|
6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00001233
|
1374 | CPT1A, CPT1, CPT1-L, L-CPT1 | carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) |
C00001233
|
1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00001233
|
2876 | GPX1, GPXD, GSHPX1 | glutathione peroxidase 1 (EC:1.11.1.9) |
C00001233
|
3034 | HAL, HIS, HSTD | histidine ammonia-lyase (EC:4.3.1.3) |
C00001233
|
57817 | HAMP, HEPC, HFE2B, LEAP1, PLTR | hepcidin antimicrobial peptide |
C00001233
|
3481 | IGF2, C11orf43, IGF-II, PP9974 | insulin-like growth factor 2 (somatomedin A) |
C00001233
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001233
|
3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00001233
|
1432 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA | mitogen-activated protein kinase 14 (EC:2.7.11.24) |
C00001233
|
5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00001233
|
5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00001233
|
4493 | MT1E, MT1, MTD | metallothionein 1E |
C00001233
|
4494 | MT1F, MT1 | metallothionein 1F |
C00001233
|
4496 | MT1H, MT-0, MT-1H, MT-IH, MT1 | metallothionein 1H |
C00001233
|
4501 | MT1X, MT-1l, MT1 | metallothionein 1X |
C00001233
|
4502 | MT2A, MT2 | metallothionein 2A |
C00001233
|
4843 | NOS2, HEP-NOS, INOS, NOS, NOS2A | nitric oxide synthase 2, inducible (EC:1.14.13.39) |
C00001233
|
3651 | PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1 | pancreatic and duodenal homeobox 1 |
C00001233
|
5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00001233
|
10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00001233
|
29893 | PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP | PSMC3 interacting protein |
C00001233
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001233
|
5054 | SERPINE1, PAI, PAI-1, PAI1, PLANH1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
C00001233
|
6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00001233
|
23216 | TBC1D1, TBC, TBC1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
C00001233
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00001233
|
7351 | UCP2, BMIQ4, SLC25A8, UCPH | uncoupling protein 2 (mitochondrial, proton carrier) |
C00001233
|
OMIM | preferred title | UniProt |
---|---|---|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#613546 | Aromatase deficiency |
P11511
|
#139300 | Aromatase excess syndrome; aexs |
P11511
|
#615363 | Estrogen resistance; estrr |
P03372
|
#612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
#246300 | Leprosy, susceptibility to, 3; lprs3 |
O60603
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
KEGG | name | UniProt |
---|---|---|
H00344 | Leprosy |
O60603
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
|
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
H00024 | Prostate cancer |
P10275
(related)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00794 | Aromatase excess syndrome |
P11511
(related)
|