Goniothalamus cardiopetalus

• Index
• Plant Species
• Metabolite list (8)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Goniothalamus cardiopetalus
Genus	Goniothalamus
Family	Annonaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Goniothalamus
Linked NCBI taxonomy ID	261082
Linked level	genus

Family

Family in NCBI taxonomy	Annonaceae
ID	22140

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Metabolite list (8)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001323	Squamocin	CHEMBL41177 CHEMBL502366 CHEMBL453405 CHEMBL452936	C059660			No. 6	No. 70
C00036528	34-epi-Goniodonin	CHEMBL451942 CHEMBL504552				No. 6	No. 70
C00037208	Goniodonin	CHEMBL451942 CHEMBL504552				No. 6	No. 70
C00037209	Goniofufurone / (+)-Goniofufurone	CHEMBL449995 CHEMBL491223 CHEMBL1171386				No. 960
C00037210	Goniofupyrone / (-)-Goniofupyrone	CHEMBL597723				No. 960
C00037207	Goniodiol / (+)-Goniodiol	CHEMBL490371				No. 3038
C00037211	Goniothalamin / (+)-Goniothalamin	CHEMBL464443 CHEMBL1170485 CHEMBL1240592	C103280	22 / 32 / 24	16 / 0	No. 3123	No. 63
C00036879	Cardiobutanolide / (+)-Cardiobutanolide					No. 4165

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q99700	Ataxin-2	Unclassified protein	C00037211	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00037211	2 / 0
P02545	Prelamin-A/C	Unclassified protein	C00037211	11 / 10
P42858	Huntingtin	Unclassified protein	C00037211	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00037211	2 / 0
O75496	Geminin	Unclassified protein	C00037211	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00037211	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00037211	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00037211	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00037211	0 / 0
O60674	Tyrosine-protein kinase JAK2	Jakb	C00037211	5 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00037211	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00037211	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00037211	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00037211	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00037211	0 / 0
O14980	Exportin-1	Unclassified protein	C00037211	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00037211	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00037211	1 / 0
O00255	Menin	Unclassified protein	C00037211	2 / 5
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00037211	2 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00037211	1 / 1

16 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
306	ANXA3, ANX3	annexin A3 (EC:3.1.4.43)	C00037211
581	BAX, BCL2L4	BCL2-associated X protein	C00037211
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00037211
835	CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57	caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55)	C00037211
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00037211
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00037211
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00037211
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00037211
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00037211
4842	NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS	nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)	C00037211
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00037211
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00037211
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00037211
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00037211
7132	TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60	tumor necrosis factor receptor superfamily, member 1A	C00037211
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00037211

Related Diseases

Diseases related to proteins in ChEMBL interactions