KNApSAcK Entry

Organism name Marrubium vulgare
Genus Marrubium
Family Labiatae
Kingdom Plantae

NCBI taxonomy


Linked NCBI taxonomy name Marrubium vulgare
Linked NCBI taxonomy ID 41230
Linked level species


Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (15)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
C00004316 External link 512 Luteolin 7-(6''-acetylglucoside)
No. 2 No. 15
C00004322 External link 512 Luteolin 7-(2''-glucuronosyllactate)
No. 2 No. 15
C00004321 External link 512 Luteolin 7-(2''-glucosyllactate)
No. 2 No. 15
C00004182 External link 512 Apigenin 7-(2''-glucuronosyllactate)
No. 2 No. 15
C00004181 External link 512 Apigenin 7-(2''-glucosyllactate)
No. 2 No. 15
C00036138 External link 512 Marruboside
/ (-)-Marruboside
No. 33
C00036042 External link 512 Ballotetroside
No. 33
C00023321 External link 512 Vulgarol
No. 118 No. 46
C00003476 External link 512 (13R)-Premarrubiin
No. 689 No. 41
C00023347 External link 512 (13S)-Premarrubiin
No. 689 No. 41
C00003452 External link 512 Marrubiin
5 / 1 / 4 No. 874 No. 41
C00022294 External link 512 Marrubenol
No. 1134
C00004180 External link 512 Apigenin 7-lactate
No. 2389
C00004320 External link 512 Luteolin 7-lactate
No. 2389
C00001345 External link 512 (-)-Betonicine
/ 4-Hydroxyproline betaine
7 / 16 / 14 No. 2627 No. 1

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001345 1 / 0
P02545 Prelamin-A/C Unclassified protein C00001345 11 / 10
P10828 Thyroid hormone receptor beta NR1A2 C00001345 3 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001345 0 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003452 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001345 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003452 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001345 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001345 0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00003452 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00003452 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00003452 1 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#275210 Restrictive dermopathy, lethal P02545
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828


KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)