Species

KNApSAcK Entry

Organism name Amorphophallus spp.
Genus Amorphophallus
Family Araceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Amorphophallus
Linked NCBI taxonomy ID 74663
Linked level genus

Family

Family in NCBI taxonomy Araceae
ID 4454

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001418 External link 512 Indole
CHEMBL15844
C030374
13 / 5 / 6 6 / 0 No. 3673

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00918 Carbonic anhydrase 2 Lyase C00001418 1 / 2
Q00535 Cyclin-dependent kinase 5 Cdk5 C00001418 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00001418 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00001418 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00001418 0 / 0
P55263 Adenosine kinase Enzyme C00001418 1 / 0
P23141 Liver carboxylesterase 1 Enzyme C00001418 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00001418 1 / 1
P05107 Integrin beta-2 Membrane receptor C00001418 1 / 1
P05362 Intercellular adhesion molecule 1 Adhesion C00001418 1 / 2
P20701 Integrin alpha-L Membrane receptor C00001418 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00001418 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00001418 0 / 0

6 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001418
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00001418
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00001418
4159 MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL melanocortin 3 receptor C00001418
4160 MC4R melanocortin 4 receptor C00001418
4161 MC5R, MC2 melanocortin 5 receptor C00001418

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#614300 Hypermethioninemia due to adenosine kinase deficiency P55263
#116920 Leukocyte adhesion deficiency, type i; lad P05107
#611162 Malaria, susceptibility to P05362
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748

KEGG DISEASE (6)

KEGG name UniProt
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00099 Leukocyte adhesion deficiency (LAD) P05107 (related)
H00083 Allograft rejection P05362 (related)
H00080 Systemic lupus erythematosus P05362 (marker)
H00527 Retinitis pigmentosa (RP) P22748 (related)