Ophiorrhiza pumila

• Index
• Plant Species
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Ophiorrhiza pumila
Genus	Ophiorrhiza
Family	Rubiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Ophiorrhiza pumila
Linked NCBI taxonomy ID	157934
Linked level	species

Family

Family in NCBI taxonomy	Rubiaceae
ID	24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00036264	3(S)-Deoxypumiloside					No. 577	No. 4
C00032210	Strictosamide	CHEMBL480522				No. 577	No. 4
C00029323	Deoxypumiloside / 3(R)-Deoxypumiloside / (3R)-Deoxypumiloside					No. 577	No. 4
C00031110	Pumiloside					No. 577	No. 4
C00029058	Strictosidine	CHEMBL402211	C021093			No. 618	No. 4
C00001434	Tryptamine / beta-(3-Indolyl)ethylamine	CHEMBL6640	C030820	20 / 5 / 7	6 / 2	No. 710	No. 4
C00003098	Secologanin	CHEMBL1235867 CHEMBL1971881	C021086	1 / 0 / 0		No. 806	No. 36
C00029611	9-Methoxycamptothecin	CHEMBL91945 CHEMBL522112		1 / 0 / 0		No. 3696	No. 7
C00029925	Chaboside					No. 8137

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001434	1 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001434	0 / 0
P28222	5-hydroxytryptamine receptor 1B	Serotonin receptor	C00001434	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001434	0 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001434	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00029611	0 / 0
P05164	Myeloperoxidase	Enzyme	C00001434	1 / 2
P43235	Cathepsin K	C1A	C00001434	1 / 2
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00001434	0 / 0
O75496	Geminin	Unclassified protein	C00001434	0 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00001434	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001434	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001434	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001434	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001434	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00001434	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001434	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001434	0 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00001434	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001434	0 / 0
P28221	5-hydroxytryptamine receptor 1D	Serotonin receptor	C00001434	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00003098	0 / 0

6 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00001434
3356	HTR2A, 5-HT2A, HTR2	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	C00001434
6530	SLC6A2, NAT1, NET, NET1, SLC6A5	solute carrier family 6 (neurotransmitter transporter), member 2	C00001434
6531	SLC6A3, DAT, DAT1, PKDYS	solute carrier family 6 (neurotransmitter transporter), member 3	C00001434
6532	SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT	solute carrier family 6 (neurotransmitter transporter), member 4	C00001434
134864	TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1	trace amine associated receptor 1	C00001434

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions