Papaver nudicaule
Species
KNApSAcK Entry
| Organism name | Papaver nudicaule |
|---|---|
| Genus | Papaver |
| Family | Papaveraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Papaver nudicaule |
|---|---|
| Linked NCBI taxonomy ID | 74823 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Papaveraceae |
|---|---|
| ID | 3465 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (8)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006759
|
Palargonidin 3-(6''-malonylsophoroside)
|
No. 1 | No. 15 |
|
||||
|
C00005165
|
Sophoraflavonoloside
/ Kaempferol 3-O-sophoroside / Kaempferol 3-O-beta-sophoroside |
CHEMBL500233
CHEMBL1375795 CHEMBL2032411 |
C064309
|
12 / 2 / 2 | 6 / 4 | No. 1 | No. 15 |
|
|
C00005688
|
Gossypetin 7-glucoside
|
No. 2 | No. 15 |
|
||||
|
C00006649
|
Pelargonidin 3-sophoroside-7-glucoside
|
No. 5 | No. 15 |
|
||||
|
C00034867
|
Kaempferol 3-O-beta-[(6-malonyl)sophoroside]-7-O-beta-glucoside
|
No. 5 | No. 15 |
|
||||
|
C00001442
|
Dhurrin
|
CHEMBL469825
|
C011220
|
No. 45 | No. 72 |
|
||
|
C00024623
|
Chelidonin
/ Stylophorine / (+)-Chelidonine |
CHEMBL436279
CHEMBL496867 CHEMBL1394506 CHEMBL2009780 |
C062047
|
8 / 19 / 21 | 1 / 2 | No. 233 | No. 4 |
|
|
C00025464
|
Rhoeagenine
|
No. 305 |
|
Human Protein / Gene in interactions
20 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00024623 | 1 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00005165 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00005165 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00005165 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00024623 | 11 / 10 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00024623 | 3 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00024623 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00005165 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00005165 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00005165 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00005165 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00024623 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00024623 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00005165 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00005165 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00005165 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00005165 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00005165 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00024623 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00024623 | 1 / 2 |
7 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4137 | MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU | microtubule-associated protein tau |
C00024623
|
| 3146 | HMGB1, HMG1, HMG3, SBP-1 | high mobility group box 1 |
C00005165
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00005165
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00005165
|
| 7097 | TLR2, CD282, TIL4 | toll-like receptor 2 |
C00005165
|
| 7099 | TLR4, ARMD10, CD284, TLR-4, TOLL | toll-like receptor 4 |
C00005165
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00005165
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (21)
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (23)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|