PCIDB

Agaricus campestris

Species

KNApSAcK Entry

Organism name Agaricus campestris
Genus Agaricus
Family Agaricaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Agaricus campestris
Linked NCBI taxonomy ID 56157
Linked level species

Family

Family in NCBI taxonomy Agaricaceae
ID 5339

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00003652 External link 512 Ergosterol
/ Ergosta-5,7,22-trien-3beta-ol
CHEMBL222608
CHEMBL1232562
CHEMBL1512075
CHEMBL1741735
CHEMBL1965225
D004875
12 / 14 / 11 No. 111 No. 11
C00023805 External link 512 Eburicol
/ Obtusifoldienol
/ 24-Methylene dihydrolanosterol
/ 24-Methylene-24,25-dihydrolanosterol
CHEMBL518556
C014520
No. 218 No. 51
C00003657 External link 512 Lanosterol
/ Lanosta-8,24-dien-3beta-ol
CHEMBL225111
CHEMBL465181
CHEMBL1397369
D007810
10 / 17 / 17 1 / 0 No. 218 No. 51
C00001525 External link 512 Agaritine
C015654
No. 8778

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11473 Vitamin D3 receptor NR1I1 C00003652 C00003657 2 / 3
P10636 Microtubule-associated protein tau Unclassified protein C00003652 C00003657 4 / 3
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003652 C00003657 0 / 1
P16050 Arachidonate 15-lipoxygenase Enzyme C00003652 C00003657 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003652 C00003657 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00003652 C00003657 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003652 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003652 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003652 1 / 0
Q16850 Lanosterol 14-alpha demethylase Cytochrome P450 51A1 C00003657 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003652 1 / 1
P02545 Prelamin-A/C Unclassified protein C00003657 11 / 10
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00003652 5 / 1
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00003657 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00003657 0 / 0
P31939 Bifunctional purine biosynthesis protein PURH Enzyme C00003652 1 / 1

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1593 CYP27A1, CP27, CTX, CYP27 cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15) C00003657

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (25)

OMIM preferred title UniProt
#608688 Aicar transformylase/imp cyclohydrolase deficiency P31939
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#143500 Gilbert syndrome P22309
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (21)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00966 AICA-ribosiduria P31939 (related)
H01171 Poor drug metabolism (PM) P33261 (related)