Artemisia dracunculus
Species
KNApSAcK Entry
| Organism name | Artemisia dracunculus |
|---|---|
| Genus | Artemisia |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Artemisia dracunculus |
|---|---|
| Linked NCBI taxonomy ID | 72341 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (17)
| Species | Activity |
|---|---|
| Artemisia dracunculus | Allergenic |
| Artemisia dracunculus | Analgesic |
| Artemisia dracunculus | Antibacterial |
| Artemisia dracunculus | Anticapillary Fragility |
| Artemisia dracunculus | Antiinflammatory |
| Artemisia dracunculus | Antipyretic |
| Artemisia dracunculus | Antispasmodic |
| Artemisia dracunculus | Aperitif |
| Artemisia dracunculus | Carminative |
| Artemisia dracunculus | Diuretic |
| Artemisia dracunculus | Emmenagogue |
| Artemisia dracunculus | Fungicide |
| Artemisia dracunculus | Genotoxic |
| Artemisia dracunculus | Hypnotic |
| Artemisia dracunculus | Stomachic |
| Artemisia dracunculus | Tumorigenic |
| Artemisia dracunculus | Vermifuge |
Metabolite list (17)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005645
|
Patuletin-3-robinobioside
|
CHEMBL442920
CHEMBL2037043 |
No. 1 | No. 15 |
|
|||
|
C00005647
|
Patuletin-3-rutinoside
/ Patuletin 3-O-rutinoside |
CHEMBL442920
CHEMBL2037043 |
No. 1 | No. 15 |
|
|||
|
C00000149
|
Spathulenol
|
CHEMBL518542
CHEMBL1774433 |
C013258
|
No. 1603 |
|
|||
|
C00028813
|
Pellitorine
|
C008778
|
No. 1863 |
|
||||
|
C00000330
|
Capillarin
|
CHEMBL479330
|
2 / 0 / 0 | No. 1865 |
|
|||
|
C00043284
|
Artemidinol
|
CHEMBL471176
|
No. 1865 |
|
||||
|
C00043224
|
8-Hydroxyartemidin
|
CHEMBL446590
|
No. 1865 |
|
||||
|
C00043132
|
(+)-(R)-(E)-3'-Hydroxyartemidin
|
CHEMBL479324
|
No. 1865 |
|
||||
|
C00043462
|
Dracumerin
|
CHEMBL460603
|
No. 1865 |
|
||||
|
C00002757
|
4-Methoxycinnamaldehyde
/ p-Methoxycinnamaldehyde |
CHEMBL452173
|
No. 2748 | No. 6 |
|
|||
|
C00037547
|
Neopellitorine B
|
No. 3056 |
|
|||||
|
C00043285
|
Artemidiol
|
CHEMBL469720
CHEMBL469721 |
No. 3264 |
|
||||
|
C00043133
|
(+)-(S,R)-Epoxyartemidin
|
CHEMBL464936
CHEMBL469503 |
No. 3264 |
|
||||
|
C00043129
|
(-)-(R)-2'-Methoxydihydroartemidin
|
CHEMBL463082
|
No. 3264 |
|
||||
|
C00037546
|
Neopellitorine A
|
No. 3616 |
|
|||||
|
C00002740
|
Estragol
/ Esdragol / Estragole |
CHEMBL470671
|
C007633
|
10 / 16 / 43 | 3 / 5 | No. 3933 | No. 6 |
|
|
C00043350
|
Capillarin isovalerate
|
CHEMBL479331
|
No. 7592 |
|
Human Protein / Gene in interactions
11 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000330 C00002740 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00002740 | 2 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00002740 | 3 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002740 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002740 | 7 / 37 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002740 | 4 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002740 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002740 | 0 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000330 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002740 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002740 | 1 / 4 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00002740
|
| 1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00002740
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00002740
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (16)
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114500 | Colorectal cancer; crc |
P18054
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #211980 | Lung cancer |
P04637
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
KEGG DISEASE (43)
| KEGG | name | UniProt |
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|