Crinum latifolium
Species
KNApSAcK Entry
| Organism name | Crinum latifolium |
|---|---|
| Genus | Crinum |
| Family | Amaryllidaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Crinum latifolium |
|---|---|
| Linked NCBI taxonomy ID | 209099 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Amaryllidaceae |
|---|---|
| ID | 4668 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (18)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005685
|
Gossypetin 3-galactoside
|
No. 2 | No. 15 |
|
||||
|
C00024429
|
Powellin
/ Powelline |
No. 103 | No. 4 |
|
||||
|
C00024355
|
Yemenine A
/ 3-O-Acetyl hamayne |
CHEMBL469438
|
No. 103 | No. 4 |
|
|||
|
C00024402
|
Latisoline
/ 9,10-Di-O-methyl-4-O-beta-D-glucopyranosylnorbelladine |
No. 122 | No. 15 |
|
||||
|
C00024400
|
Latifine
/ (-)-Latifine |
No. 253 | No. 4 |
|
||||
|
C00024385
|
Crinine
|
No. 253 | No. 4 |
|
||||
|
C00024372
|
Cheryllin
/ Cherylline / (-)-Cherylline / (S)-(-)-Cherylline / Crinine(C17 alkaloid) |
No. 253 | No. 4 |
|
||||
|
C00001572
|
Hippeastrine
|
CHEMBL457606
CHEMBL1333401 CHEMBL1515264 |
C060577
|
8 / 3 / 4 | No. 715 |
|
||
|
C00024348
|
1,2-beta-Epoxyambelline
/ 1beta,2beta-Epoxyambelline |
No. 830 | No. 4 |
|
||||
|
C00024440
|
Undulatin
/ Undulatine |
No. 830 | No. 4 |
|
||||
|
C00024351
|
1-O-Acetyllycorine
|
CHEMBL251077
CHEMBL1998160 |
2 / 1 / 1 | No. 860 | No. 4 |
|
||
|
C00024430
|
Pratorimine
|
No. 1055 |
|
|||||
|
C00028857
|
Pratosine
|
No. 1055 |
|
|||||
|
C00024395
|
Hippadine
/ Pratorine |
CHEMBL1922244
|
C039688
|
No. 1055 |
|
|||
|
C00024431
|
Pratorinine
|
No. 1055 |
|
|||||
|
C00024432
|
Pratosine
|
No. 1055 |
|
|||||
|
C00001576
|
Lycorine
/ (-)-Lycorine |
CHEMBL224745
CHEMBL400092 CHEMBL583716 CHEMBL577635 CHEMBL1592744 CHEMBL1593638 |
C015330
|
20 / 24 / 18 | 5 / 5 | No. 1156 | No. 4 |
|
|
C00024401
|
Latisodine
/ 4-[2-(3,4-Dimethoxybenzylamino)ethyl]phenol |
No. 4021 |
|
Human Protein / Gene in interactions
21 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001572 C00001576 C00024351 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001572 C00001576 | 1 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001572 C00001576 | 1 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001572 C00001576 | 1 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001572 C00001576 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001572 C00001576 | 0 / 1 |
| P22303 | Acetylcholinesterase | Hydrolase | C00001576 C00024351 | 1 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001572 C00001576 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001576 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001572 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00001576 | 2 / 3 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001576 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00001576 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00001576 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001576 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001576 | 11 / 10 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001576 | 2 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001576 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00001576 | 4 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001576 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001576 | 1 / 1 |
5 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 896 | CCND3 | cyclin D3 |
C00001576
|
| 1003 | CDH5, 7B4, CD144 | cadherin 5, type 2 (vascular endothelium) |
C00001576
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001576
|
| 10507 | SEMA4D, C9orf164, CD100, M-sema-G, SEMAJ, coll-4 | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
C00001576
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00001576
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (24)
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (18)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |