PCIDB

Aconitum longtounens T.L.Ming.

Organism name	Aconitum longtounens T.L.Ming.
Genus	Aconitum
Family	Ranunculaceae
Kingdom	Plantae

Family in NCBI taxonomy	Ranunculaceae
ID	3440

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	eudicotyledons
ID	71240

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	KCF-S cluster	phytochemical cluster
C00001632	Delcosine	CHEMBL2141282		2 / 7 / 3	No. 31	No. 10
C00001634	Delsoline	CHEMBL1242534 CHEMBL1474356 CHEMBL2112855	C045308	8 / 15 / 13	No. 31	No. 10
C00028037	Chasmaconitine				No. 138	No. 10
C00028276	Foresaconitine / Vilmorrianine C				No. 138	No. 10

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00001632 C00001634	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001634	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001634	0 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00001634	2 / 0
P02545	Prelamin-A/C	Unclassified protein	C00001634	11 / 10
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001632	7 / 3
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001634	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001634	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001634	0 / 1

OMIM	preferred title	UniProt
#219080	Acth-independent macronodular adrenal hyperplasia; aimah	P63092
#115200	Cardiomyopathy, dilated, 1a; cmd1a	P02545
#212112	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	P02545
#605588	Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1	P02545
#114500	Colorectal cancer; crc	P84022
#609535	Drug metabolism, poor, cyp2c19-related	P33261
#608902	Drug metabolism, poor, cyp2d6-related	P10635
#181350	Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2	P02545
#610140	Heart-hand syndrome, slovenian type	P02545
#176670	Hutchinson-gilford progeria syndrome; hgps	P02545
#151660	Lipodystrophy, familial partial, type 2; fpld2	P02545
#613795	Loeys-dietz syndrome, type 3; lds3	P84022
#248370	Mandibuloacral dysplasia with type a lipodystrophy; mada	P02545
#174800	Mccune-albright syndrome; mas	P63092
#613205	Muscular dystrophy, congenital, lmna-related	P02545
#159001	Muscular dystrophy, limb-girdle, type 1b; lgmd1b	P02545
#166350	Osseous heteroplasia, progressive; poh	P63092
#102200	Pituitary adenoma, growth hormone-secreting	P63092
#103580	Pseudohypoparathyroidism, type ia; php1a	P63092
#603233	Pseudohypoparathyroidism, type ib; php1b	P63092
#612462	Pseudohypoparathyroidism, type ic; php1c	P63092
#275210	Restrictive dermopathy, lethal	P02545

KEGG	name	UniProt
H00264	Charcot-Marie-Tooth disease (CMT)	P02545 (related)
H00294	Dilated cardiomyopathy (DCM)	P02545 (related)
H00420	Familial partial lipodystrophy (FPL)	P02545 (related)
H00563	Emery-Dreifuss muscular dystrophy	P02545 (related)
H00590	Congenital muscular dystrophies (CMD/MDC)	P02545 (related)
H00593	Limb-girdle muscular dystrophy (LGMD)	P02545 (related)
H00601	Hutchinson-Gilford progeria syndrome	P02545 (related)
H00663	Restrictive dermopathy	P02545 (related)
H00665	Mandibuloacral dysplasia	P02545 (related)
H01216	Left ventricular noncompaction (LVNC)	P02545 (related)
H00036	Osteosarcoma	P08684 (marker)
H01205	Coumarin resistance	P11712 (related)
H01171	Poor drug metabolism (PM)	P33261 (related)
H00244	Pseudohypoparathyroidism	P63092 (related)
H00441	Progressive osseous heteroplasia (POH)	P63092 (related)
H00501	Fibrous dysplasia, polyostotic	P63092 (related)