PCIDB

Leptactina densiflora

Species

KNApSAcK Entry

Organism name Leptactina densiflora
Genus Leptactina
Family Rubiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Leptactina
Linked NCBI taxonomy ID 58475
Linked level genus

Family

Family in NCBI taxonomy Rubiaceae
ID 24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00001774 External link 512 Tetrahydroharmine
CHEMBL129208
C035525
17 / 10 / 14 No. 2351 No. 4

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001774 0 / 0
P06746 DNA polymerase beta Enzyme C00001774 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00001774 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001774 0 / 0
P47898 5-hydroxytryptamine receptor 5A Serotonin receptor C00001774 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00001774 2 / 2
P39748 Flap endonuclease 1 Enzyme C00001774 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001774 1 / 1
P08253 72 kDa type IV collagenase M10A C00001774 1 / 3
Q9UNA4 DNA polymerase iota Enzyme C00001774 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001774 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001774 4 / 3
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001774 0 / 0
O00487 26S proteasome non-ATPase regulatory subunit 14 Enzyme C00001774 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001774 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001774 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001774 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (14)

KEGG name UniProt
H00025 Penile cancer P08253 (related)
H00028 Choriocarcinoma P08253 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)