| Organism name | Alangium kurzii |
|---|---|
| Genus | Alangium |
| Family | Cornaceae / Aucubaceae / Garryaceae / Helwingiaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Alangium kurzii |
|---|---|
| Linked NCBI taxonomy ID | 161874 |
| Linked level | species |
| Family in NCBI taxonomy | Cornaceae |
|---|---|
| ID | 42219 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00001798
|
Alangiside
|
CHEMBL486383
CHEMBL2138751 |
2 / 0 / 0 | No. 577 | No. 4 |
|
||
|
C00028162
|
Demethylalangiside
|
No. 577 | No. 4 |
|
||||
|
C00002015
|
(-)-Anabasine
|
CHEMBL280963
CHEMBL1496898 CHEMBL1526229 |
D000691
|
15 / 18 / 15 | 0 / 4 | No. 2084 | No. 1 |
|
|
C00001805
|
Ankorine
|
No. 2276 | No. 4 |
|
||||
|
C00019674
|
Uridine
|
CHEMBL68846
CHEMBL100259 CHEMBL265701 CHEMBL608294 CHEMBL609651 CHEMBL1092065 CHEMBL2093066 |
D014529
|
5 / 0 / 3 | 7 / 15 | No. 2366 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00001798 C00019674 | 0 / 0 |
| Q9HA47 | Uridine-cytidine kinase 1 | Enzyme | C00019674 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00019674 | 0 / 3 |
| P06746 | DNA polymerase beta | Enzyme | C00002015 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002015 | 0 / 1 |
| P17787 | Neuronal acetylcholine receptor subunit beta-2 | CHRN beta | C00002015 | 1 / 1 |
| P43681 | Neuronal acetylcholine receptor subunit alpha-4 | CHRN alpha | C00002015 | 1 / 1 |
| P27708 | CAD protein | Enzyme | C00019674 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002015 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002015 | 1 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002015 | 4 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002015 | 7 / 3 |
| P36544 | Neuronal acetylcholine receptor subunit alpha-7 | CHRN alpha | C00002015 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002015 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002015 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002015 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00019674 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002015 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00002015 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002015 | 1 / 2 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001798 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00019674
|
| 2993 | GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 | glycophorin A (MNS blood group) |
C00019674
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00019674
|
| 9154 | SLC28A1, CNT1, HCNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
C00019674
|
| 9153 | SLC28A2, CNT2, HCNT2, HsT17153, SPNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 2 |
C00019674
|
| 2030 | SLC29A1, ENT1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
C00019674
|
| 3177 | SLC29A2, DER12, ENT2, HNP36 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
C00019674
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #600513 | Epilepsy, nocturnal frontal lobe, 1; enfl1 |
P43681
|
| #605375 | Epilepsy, nocturnal frontal lobe, 3; enfl3 |
P17787
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00807 | Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) |
P17787
(related)
P43681 (related) |
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001259 | Ataxia |
C00002015
|
| D006948 | Hyperkinesis |
C00002015
|
| D018908 | Muscle Weakness |
C00002015
|
| D014202 | Tremor |
C00002015
|
| D000015 | Abnormalities, Multiple |
C00019674
|
| D000749 | Anemia, Megaloblastic |
C00019674
|
| D001919 | Bradycardia |
C00019674
|
| D002375 | Catalepsy |
C00019674
|
| D004342 | Drug Hypersensitivity |
C00019674
|
| D056486 | Drug-Induced Liver Injury |
C00019674
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00019674
|
| D005234 | Fatty Liver |
C00019674
|
| D007022 | Hypotension |
C00019674
|
| D028361 | Mitochondrial Diseases |
C00019674
|
| C538525 | Mitochondrial encephalopathy |
C00019674
|
| D017240 | Mitochondrial Myopathies |
C00019674
|
| D010523 | Peripheral Nervous System Diseases |
C00019674
|
| D011565 | Psoriasis |
C00019674
|
| D019956 | Stereotypic Movement Disorder |
C00019674
|