Species

KNApSAcK Entry

Organism name Atherosperma moschatum
Genus Atherosperma
Family Monimiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Atherosperma moschatum
Linked NCBI taxonomy ID 88856
Linked level species

Family

Family in NCBI taxonomy Atherospermataceae
ID 88854

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001817 External link 512 Berbamine
/ d-Berbamine
/ (+)-Berbamine
CHEMBL504323
CHEMBL507540
CHEMBL1198334
C027870
4 / 3 / 4 9 / 1 No. 10 No. 4
C00001814 External link 512 (+)-Atherospermoline
No. 10 No. 4
C00001813 External link 512 Atherospermidine
C064684
No. 74
C00001812 External link 512 Atheroline
C001827
No. 74

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P54750 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE_1A C00001817 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001817 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001817 3 / 3
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001817 0 / 1

9 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00001817
637 BID, FP497 BH3 interacting domain death agonist C00001817
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00001817
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00001817
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00001817
1147 CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) C00001817
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00001817
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00001817
7128 TNFAIP3, A20, OTUD7C, TNFA1P2 tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) C00001817

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714

KEGG DISEASE (4)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D015473 Leukemia, Promyelocytic, Acute C00001817