Zanthoxylum veneficum
Species
KNApSAcK Entry
| Organism name | Zanthoxylum veneficum |
|---|---|
| Genus | Zanthoxylum |
| Family | Rutaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Zanthoxylum brachyacanthum |
|---|---|
| Linked NCBI taxonomy ID | 1056464 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001827
|
Canadine
/ Xanthopuccine / Tetrahydroberberine / Tetrahydroumbellatine |
CHEMBL275097
CHEMBL490533 CHEMBL476501 |
C004645
|
22 / 36 / 28 | No. 37 | No. 4 |
|
Human Protein / Gene in interactions
22 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001827 | 1 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001827 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001827 | 1 / 1 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001827 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001827 | 11 / 10 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00001827 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001827 | 0 / 1 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00001827 | 2 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001827 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00001827 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00001827 | 7 / 3 |
| P13726 | Tissue factor | Membrane receptor | C00001827 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001827 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00001827 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001827 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001827 | 0 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001827 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00001827 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00001827 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001827 | 1 / 2 |
| Q14654 | ATP-sensitive inward rectifier potassium channel 11 | K | C00001827 | 3 / 4 |
| Q09428 | ATP-binding cassette sub-family C member 8 | K | C00001827 | 5 / 3 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (36)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #103780 | Alcohol dependence |
P14416
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #606176 | Diabetes mellitus, permanent neonatal; pndm |
Q09428
Q14654 |
| #610374 | Diabetes mellitus, transient neonatal, 2 |
Q09428
|
| #610582 | Diabetes mellitus, transient neonatal, 3 |
Q14654
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #256450 | Hyperinsulinemic hypoglycemia, familial, 1; hhf1 |
Q09428
|
| #601820 | Hyperinsulinemic hypoglycemia, familial, 2; hhf2 |
Q14654
|
| #602485 | Hyperinsulinemic hypoglycemia, familial, 3; hhf3 |
Q09428
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #240800 | Hypoglycemia, leucine-induced; lih |
Q09428
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #159900 | Myoclonic dystonia |
P14416
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG DISEASE (28)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00512 | Permanent neonatal diabetes mellitus (PNDM) |
Q09428
(related)
Q14654 (related) |
| H00513 | Transient neonatal diabetes mellitus (TNDM) |
Q09428
(related)
Q14654 (related) |
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
Q09428
(related)
Q14654 (related) |
| H00409 | Type II diabetes mellitus |
Q14654
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|