Thalictrum alpinum L.
Species
KNApSAcK Entry
| Organism name | Thalictrum alpinum L. |
|---|---|
| Genus | Thalictrum |
| Family | Ranunculaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Thalictrum alpinum |
|---|---|
| Linked NCBI taxonomy ID | 395328 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Ranunculaceae |
|---|---|
| ID | 3440 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (4)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001866
|
Hernandezine
|
CHEMBL504936
|
C067193
|
5 / 4 / 8 | No. 10 | No. 4 |
|
|
|
C00024667
|
Columbamine
/ Dehydroisocorypalmine |
CHEMBL400345
|
C055786
|
1 / 0 / 1 | 8 / 1 | No. 155 | No. 4 |
|
|
C00026154
|
Thalifendine
|
CHEMBL1187148
|
C477156
|
No. 155 | No. 4 |
|
||
|
C00025997
|
Berlambine
/ Oxyberberine / 8-Oxoberberine |
CHEMBL11531
|
No. 439 |
|
Human Protein / Gene in interactions
6 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11473 | Vitamin D3 receptor | NR1I1 | C00001866 | 2 / 3 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00024667 | 0 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001866 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001866 | 1 / 1 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001866 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001866 | 1 / 4 |
8 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1003 | CDH5, 7B4, CD144 | cadherin 5, type 2 (vascular endothelium) |
C00024667
|
| 1021 | CDK6, PLSTIRE | cyclin-dependent kinase 6 (EC:2.7.11.22) |
C00024667
|
| 1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) |
C00024667
|
| 2048 | EPHB2, CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5 | EPH receptor B2 (EC:2.7.10.1) |
C00024667
|
| 9500 | MAGED1, DLXIN-1, NRAGE | melanoma antigen family D, 1 |
C00024667
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00024667
|
| 64321 | SOX17, VUR3 | SRY (sex determining region Y)-box 17 |
C00024667
|
| 6774 | STAT3, APRF, HIES | signal transducer and activator of transcription 3 (acute-phase response factor) |
C00024667
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (4)
| OMIM | preferred title | UniProt |
|---|---|---|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (9)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|