| Organism name | Cyclea peltata Diels |
|---|---|
| Genus | Cyclea |
| Family | Menispermaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Cyclea |
|---|---|
| Linked NCBI taxonomy ID | 152372 |
| Linked level | genus |
| Family in NCBI taxonomy | Menispermaceae |
|---|---|
| ID | 3455 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00001870
|
Isobebeerin
/ Isobebeerine / Isochondodendrine |
CHEMBL509310
CHEMBL1169628 |
No. 10 | No. 4 |
|
|||
|
C00025265
|
Homoaromoline
/ Homothalicrine / (+)-Homoaromoline / (+)-Thalrugosamine |
CHEMBL507220
CHEMBL503522 CHEMBL509855 CHEMBL1185978 |
No. 10 | No. 4 |
|
|||
|
C00025276
|
Thalrugosine
/ (+)-Thalrugosine |
C060802
|
0 / 1 | No. 10 | No. 4 |
|
||
|
C00025306
|
Fangchinoline
/ dl-Fangchinoline / 7-O-Demethyltetrandrine |
CHEMBL504256
CHEMBL509803 CHEMBL500614 |
12 / 6 / 3 | No. 10 | No. 4 |
|
||
|
C00025320
|
Limacine
/ (-)-Limacine |
CHEMBL504256
CHEMBL509803 CHEMBL500614 |
12 / 6 / 3 | No. 10 | No. 4 |
|
||
|
C00025571
|
Tetrandrine N-2'-oxide
/ Tetrandrine 2'beta-N-oxide / Tetrandrine mono-N-2'-oxide |
No. 10 | No. 4 |
|
||||
|
C00025594
|
2'-N-Norlimacine
/ (-)-2'-Norlimacine / 2'-Demethyllimacine / 2'-Demethyl-(-)-fangchinoline |
CHEMBL508608
|
C085399
|
No. 10 | No. 4 |
|
||
|
C00025602
|
l-Curine
/ (-)-Curine / l-Bebeerine / Aristolochine / (-)-Bebeerine / Aristolochine(C36 alkaloid) |
CHEMBL1169627
|
13 / 6 / 5 | No. 10 | No. 4 |
|
||
|
C00025831
|
Cycleacurin
/ Cycleacurine |
No. 10 | No. 4 |
|
||||
|
C00025833
|
Cycleahomine
|
No. 10 | No. 4 |
|
||||
|
C00025624
|
Repandin
/ Repandine / (-)-Repandine / N-Methyldemerarine |
CHEMBL510022
CHEMBL509999 CHEMBL1983122 |
5 / 4 / 1 | No. 10 | No. 4 |
|
||
|
C00025832
|
Cycleadrine
|
CHEMBL504256
CHEMBL509803 CHEMBL500614 |
12 / 6 / 3 | No. 10 | No. 4 |
|
||
|
C00025656
|
(+)-Cycleabarbatine
|
C085398
|
No. 10 | No. 4 |
|
|||
|
C00025605
|
Faralaotrine
/ Cycleapeltin / Cycleapeltine / (-)-Cycleapeltine |
CHEMBL507220
CHEMBL503522 CHEMBL509855 CHEMBL1185978 |
No. 10 | No. 4 |
|
|||
|
C00025652
|
d-Coclaurine
/ Sanjoinine K / (R)-Coclaurine / (+)-Coclaurine / (+)-R-Coclaurine |
CHEMBL256448
CHEMBL453291 CHEMBL446211 |
8 / 17 / 10 | No. 253 | No. 4 |
|
||
|
C00025619
|
(-)-N-Methylcoclaurine
/ (R)-N-Methylcoclaurine |
CHEMBL453292
CHEMBL513109 |
No. 253 | No. 4 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00025306 C00025320 C00025602 C00025652 C00025832 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00025306 C00025320 C00025602 C00025624 C00025832 | 1 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00025306 C00025320 C00025602 C00025624 C00025832 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00025306 C00025320 C00025624 C00025832 | 1 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00025306 C00025320 C00025624 C00025832 | 2 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00025306 C00025320 C00025832 | 0 / 1 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00025306 C00025320 C00025832 | 1 / 1 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00025306 C00025320 C00025832 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00025306 C00025320 C00025832 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00025306 C00025320 C00025832 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00025306 C00025320 C00025832 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00025306 C00025320 C00025832 | 1 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00025602 C00025652 | 4 / 3 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00025602 C00025652 | 0 / 0 |
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00025602 C00025624 | 0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00025602 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00025602 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00025652 | 7 / 3 |
| P42858 | Huntingtin | Unclassified protein | C00025602 | 1 / 1 |
| O43603 | Galanin receptor type 2 | Galanin receptor | C00025602 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00025602 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00025652 | 0 / 0 |
| P47898 | 5-hydroxytryptamine receptor 5A | Serotonin receptor | C00025602 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00025652 | 6 / 4 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00025652 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00025652 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00025602 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #143100 | Huntington disease; hd |
P42858
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|