Papaver orientale L.
Species
KNApSAcK Entry
| Organism name | Papaver orientale L. |
|---|---|
| Genus | Papaver |
| Family | Papaveraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Papaver orientale |
|---|---|
| Linked NCBI taxonomy ID | 22694 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Papaveraceae |
|---|---|
| ID | 3465 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00025459
|
Papaverrubine C
/ Epiporphyroxine / 14-Epiporphyroxine |
No. 305 |
|
|||||
|
C00025461
|
Papaverrubine E
|
No. 305 |
|
|||||
|
C00025460
|
Porphyroxine
/ Papaverrubine D |
No. 305 |
|
|||||
|
C00025449
|
Alpinigenine
|
C006478
|
No. 305 |
|
||||
|
C00025458
|
Papaverrubine B
/ O-Methylporphyroxine |
No. 305 |
|
|||||
|
C00001906
|
Fumarin
/ Biflorine / Protopine / Fumarine / Corydinine |
CHEMBL453019
|
C009093
|
5 / 5 / 4 | 2 / 0 | No. 820 | No. 4 |
|
|
C00024940
|
Orientinine
/ (+)-Orientinine / 7,11,14-Trihydroxy-2,13-dioxohetisane |
No. 1045 | No. 10 |
|
||||
|
C00001924
|
Thebaine
/ (-)-Thebaine / Paramorphine |
CHEMBL403893
CHEMBL1318110 |
D013797
|
4 / 0 / 0 | No. 1983 | No. 4 |
|
|
|
C00028775
|
Oripavine
|
CHEMBL437602
|
C005283
|
1 / 0 / 0 | No. 1983 | No. 4 |
|
|
|
C00026140
|
Bractavine
/ Orientalidine |
No. 3042 |
|
|||||
|
C00026134
|
Mecambridine
/ (-)-Oreophiline / (-)-Mecambridine |
C051429
|
No. 3042 |
|
Human Protein / Gene in interactions
9 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001924 C00028775 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001906 | 1 / 0 |
| O75496 | Geminin | Unclassified protein | C00001924 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001924 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001906 | 3 / 2 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001906 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001906 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001924 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001906 | 0 / 0 |
2 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001906
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001906
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (5)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|