Sinomenium acutum
Species
KNApSAcK Entry
| Organism name | Sinomenium acutum |
|---|---|
| Genus | Sinomenium |
| Family | Menispermaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Sinomenium acutum |
|---|---|
| Linked NCBI taxonomy ID | 152363 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Menispermaceae |
|---|---|
| ID | 3455 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001918
|
Cucoline
/ Kukoline / Sinomenine |
CHEMBL248095
CHEMBL1551847 CHEMBL1555036 CHEMBL1589951 CHEMBL1591798 |
C009271
|
9 / 8 / 8 | No. 346 | No. 4 |
|
|
|
C00025272
|
Stepharine
/ (+)-Stepharine |
CHEMBL463957
CHEMBL1975436 |
C009320
|
No. 688 |
|
|||
|
C00002310
|
Acutumidine
|
CHEMBL237548
CHEMBL237765 |
No. 915 |
|
||||
|
C00038197
|
2,2'-Disinomenine
/ (+)-2,2'-Disinomenine |
CHEMBL256341
|
No. 3422 |
|
||||
|
C00042999
|
Sinomenine N-oxide
|
No. 6279 |
|
Human Protein / Gene in interactions
9 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001918 | 1 / 0 |
| P01375 | Tumor necrosis factor | Secreted protein | C00001918 | 3 / 4 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00001918 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001918 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001918 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001918 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001918 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001918 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001918 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (8)
| OMIM | preferred title | UniProt |
|---|---|---|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #610424 | Hepatitis b virus, susceptibility to |
P01375
|
| #611162 | Malaria, susceptibility to |
P01375
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #607507 | Psoriatic arthritis, susceptibility to |
P01375
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00079 | Asthma |
P01375
(related)
|
| H00080 | Systemic lupus erythematosus |
P01375
(related)
P01375 (marker) |
| H00083 | Allograft rejection |
P01375
(related)
|
| H00084 | Graft-versus-host disease |
P01375
(related)
P01375 (marker) |
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|