Species

KNApSAcK Entry

Organism name Swertia spp.
Genus Swertia
Family Gentianaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Swertia
Linked NCBI taxonomy ID 39241
Linked level genus

Family

Family in NCBI taxonomy Gentianaceae
ID 21472

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006268 External link 512 Spinosin
C055669
No. 1 No. 15
C00006129 External link 512 Isoswertisin
/ 7-O-Methylvitexin
/ Isoflavocommelitin
/ 8-beta-D-Glucopyranosyl-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
No. 22 No. 15
C00002500 External link 512 Scopolin
CHEMBL225024
C417572
7 / 3 / 4 No. 491 No. 25
C00003070 External link 512 Amarogentin
C102609
1 / 3 No. 2478
C00001977 External link 512 Gentianine
C060402
No. 3439

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P43166 Carbonic anhydrase 7 Lyase C00002500 0 / 0
Q8N1Q1 Carbonic anhydrase 13 Lyase C00002500 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00002500 1 / 2
O43570 Carbonic anhydrase 12 Lyase C00002500 1 / 2
P00915 Carbonic anhydrase 1 Lyase C00002500 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002500 0 / 1
P22303 Acetylcholinesterase Hydrolase C00002500 1 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
259296 TAS2R50, T2R50, T2R51, TAS2R51 taste receptor, type 2, member 50 C00003070

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#143860 Hyperchlorhidrosis, isolated O43570
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#112100 Yt blood group antigen P22303

KEGG DISEASE (4)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)

Diseases related to CTD interactions

3 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D007898 Leishmaniasis, Visceral C00003070
D010212 Papilloma C00003070
D012878 Skin Neoplasms C00003070