PCIDB

Alexa grandiflora

Species

KNApSAcK Entry

Organism name Alexa grandiflora
Genus Alexa
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Alexa grandiflora
Linked NCBI taxonomy ID 1079071
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002028 External link 512 Castanospermine
CHEMBL67964
CHEMBL311226
CHEMBL421040
CHEMBL464490
CHEMBL1213468
CHEMBL1438313
CHEMBL1980354
C037806
14 / 13 / 16 No. 677 No. 2
C00036643 External link 512 7a-Epialexaflorine
No. 677 No. 2

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002028 1 / 0
P04062 Glucosylceramidase Enzyme C00002028 6 / 4
Q14697 Neutral alpha-glucosidase AB Enzyme C00002028 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00002028 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002028 0 / 1
O75496 Geminin Unclassified protein C00002028 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002028 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002028 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002028 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002028 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00002028 0 / 0
O00255 Menin Unclassified protein C00002028 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002028 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002028 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#168600 Parkinson disease, late-onset; pd P04062

KEGG DISEASE (16)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)