Species

KNApSAcK Entry

Organism name Capparis tomentosa
Genus Capparis
Family Capparaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Capparis tomentosa
Linked NCBI taxonomy ID 202775
Linked level species

Family

Family in NCBI taxonomy Capparaceae
ID 301453

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (8)

Species Activity
Capparis tomentosa Lam. Antispasmodic
Capparis tomentosa Lam. Decongestant
Capparis tomentosa Lam. Depurative
Capparis tomentosa Lam. Diuretic
Capparis tomentosa Lam. Emetic
Capparis tomentosa Lam. Expectorant
Capparis tomentosa Lam. Philtre
Capparis tomentosa Lam. Tonic

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002074 External link 512 Stachydrine
CHEMBL394450
CHEMBL1456892
CHEMBL1986864
10 / 8 / 12 No. 2627 No. 1

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002074 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00002074 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002074 0 / 1
Q92830 Histone acetyltransferase KAT2A Enzyme C00002074 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002074 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002074 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002074 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002074 0 / 1
O00255 Menin Unclassified protein C00002074 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002074 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (12)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)