PCIDB

KNApSAcK Metabolite C00002074

Metabolite

KNApSAcK Entry

id C00002074
Name Stachydrine
CAS RN 471-87-4
Standard InChI InChI=1S/C7H13NO2/c1-8(2)5-3-4-6(8)7(9)10/h6H,3-5H2,1-2H3/t6-/m0/s1
Standard InChI (Main Layer) InChI=1S/C7H13NO2/c1-8(2)5-3-4-6(8)7(9)10/h6H,3-5H2,1-2H3

Cluster

Phytochemical cluster No. 1
KCF-S cluster No. 2627

Link

ChEMBL

By standard InChI CHEMBL1456892
By standard InChI Main Layer CHEMBL394450 CHEMBL1456892 CHEMBL1986864

KEGG

By LinkDB C10172

CTD

By CAS RN

Species

Summary

Plant class

class name count
asterids 14
rosids 10
Liliopsida 1

Family

family name count
Lamiaceae 13
Capparaceae 5
Fabaceae 3
Combretaceae 1
Asteraceae 1
Xanthorrhoeaceae 1
Rutaceae 1

List (25)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Achillea millefolium 13329 Asteraceae asterids Viridiplantae
Asphodelus microcarpus 49697 Xanthorrhoeaceae Liliopsida Viridiplantae
Betonica officinalis 53173 Lamiaceae asterids Viridiplantae
Capparis aegyptia 13394 Capparaceae rosids Viridiplantae
Capparis deserti 13394 Capparaceae rosids Viridiplantae
Capparis leucophylla 13394 Capparaceae rosids Viridiplantae
Capparis spinosa L. 65558 Capparaceae rosids Viridiplantae
Capparis tomentosa 202775 Capparaceae rosids Viridiplantae
Citrus grandis 37334 Rutaceae rosids Viridiplantae
Combretum micranthum 578542 Combretaceae rosids Viridiplantae
Desmodium triflorum 670328 Fabaceae rosids Viridiplantae
Eremostachys speciosa 1138133 Lamiaceae asterids Viridiplantae
Erythrina variegata 3845 Fabaceae rosids Viridiplantae
Lagochilus inebrians Bge. 694359 Lamiaceae asterids Viridiplantae
Lagochilus pubescens 694359 Lamiaceae asterids Viridiplantae
Lagochilus setulosus 694359 Lamiaceae asterids Viridiplantae
Lamium album L. 53159 Lamiaceae asterids Viridiplantae
Leonurus turkestanicus 445401 Lamiaceae asterids Viridiplantae
Medicago sativa 3879 Fabaceae rosids Viridiplantae
Stachys balansae 1007628 Lamiaceae asterids Viridiplantae
Stachys betoniciflora 53171 Lamiaceae asterids Viridiplantae
Stachys betonicifolia 53171 Lamiaceae asterids Viridiplantae
Stachys hissarica 53171 Lamiaceae asterids Viridiplantae
Stachys lanata 53171 Lamiaceae asterids Viridiplantae
Stachys tubifera 53171 Lamiaceae asterids Viridiplantae

Human Protein / Gene in interaction

10 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1456892 CHEMBL1741321 (1)
1 / 0
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL1456892 CHEMBL1614361 (1)
3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1456892 CHEMBL1741325 (1)
0 / 1
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL1456892 CHEMBL1738606 (1)
0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL1456892 CHEMBL1794467 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1456892 CHEMBL1741322 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1456892 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1456892 CHEMBL1741324 (1)
0 / 1
O00255 Menin Unclassified protein CHEMBL1456892 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1456892 CHEMBL1614257 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (12)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)