Senecio palmatus
Species
KNApSAcK Entry
| Organism name | Senecio palmatus |
|---|---|
| Genus | Senecio |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Senecio |
|---|---|
| Linked NCBI taxonomy ID | 18794 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002117
|
Seneciphylline
|
CHEMBL523911
CHEMBL1396368 CHEMBL1439490 CHEMBL1591009 |
C013678
|
14 / 12 / 13 | No. 622 | No. 2 |
|
Human Protein / Gene in interactions
14 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002117 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002117 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00002117 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002117 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002117 | 7 / 3 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002117 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002117 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002117 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002117 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002117 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002117 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002117 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002117 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002117 | 1 / 4 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (13)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|