PCIDB

Alkanna tinctoria

Species

KNApSAcK Entry

Organism name Alkanna tinctoria
Genus Alkanna
Family Boraginaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Alkanna tinctoria
Linked NCBI taxonomy ID 543564
Linked level species

Family

Family in NCBI taxonomy Boraginaceae
ID 21571

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002124 External link 512 Triangularine
No. 623 No. 2
C00002787 External link 512 Alkannin
CHEMBL9470
CHEMBL29285
CHEMBL28457
16 / 14 / 12 No. 2968 No. 80

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35610 Sterol O-acyltransferase 1 Enzyme C00002787 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00002787 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00002787 4 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00002787 3 / 1
P11387 DNA topoisomerase 1 Isomerase C00002787 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00002787 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00002787 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002787 0 / 0
O75908 Sterol O-acyltransferase 2 Enzyme C00002787 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002787 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002787 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00002787 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00002787 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002787 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00002787 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00002787 1 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (12)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)