Isatis tinctoria L

• Index
• Plant Species
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Isatis tinctoria L
Genus	Isatis
Family	Cruciferae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Isatis
Linked NCBI taxonomy ID	161755
Linked level	genus

Family

Family in NCBI taxonomy	Brassicaceae
ID	3700

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00002200	Tryptanthrin / Tryptanthrine / Couroupitine A	CHEMBL306946	C046243	20 / 22 / 23	2 / 0	No. 1798	No. 7
C00026992	Epiglucoisatisin / (S)-Epiglucoisatisin					No. 3818
C00026991	Glucoisatisin / (R)-Glucoisatisin					No. 3818
C00026993	3'-Hydroxyepiglucoisatisin / (S)-3'-Hydroxyepiglucoisatisin					No. 3818

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002200	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002200	0 / 3
P02545	Prelamin-A/C	Unclassified protein	C00002200	11 / 10
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002200	0 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002200	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00002200	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00002200	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002200	0 / 0
P42858	Huntingtin	Unclassified protein	C00002200	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002200	2 / 0
O75496	Geminin	Unclassified protein	C00002200	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002200	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002200	1 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002200	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002200	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002200	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002200	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002200	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002200	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002200	0 / 0

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002200
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002200

Related Diseases

Diseases related to proteins in ChEMBL interactions