PCIDB

Fragaria spp.

Species

KNApSAcK Entry

Organism name Fragaria spp.
Genus Fragaria
Family Rosaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Fragaria
Linked NCBI taxonomy ID 3746
Linked level genus

Family

Family in NCBI taxonomy Rosaceae
ID 3745

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002378 External link 512 Cyanin
/ Cyanidin 3,5-diglucoside
No. 1 No. 15
C00006629 External link 512 Fragarin
No. 2 No. 15
C00009071 External link 512 Procyanidin B3
/ Catechin-(4alpha->8)-catechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
20 / 7 / 8 No. 16 No. 19
C00009070 External link 512 Procyanidin B6
/ Catechin-(4alpha->6)-catechin
CHEMBL506487
CHEMBL502984
CHEMBL451115
No. 16 No. 19
C00002477 External link 512 Imperatorin
CHEMBL453805
C031534
18 / 7 / 6 1 / 1 No. 606 No. 25

Human Protein / Gene in interactions

37 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002477 C00009071 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00009071 1 / 1
P10253 Lysosomal alpha-glucosidase Hydrolase C00002477 1 / 1
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002477 0 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00002477 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00009071 0 / 1
P11473 Vitamin D3 receptor NR1I1 C00002477 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00002477 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00002477 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002477 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002477 0 / 0
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase C00009071 0 / 0
P35236 Tyrosine-protein phosphatase non-receptor type 7 Tyr C00002477 0 / 0
P56817 Beta-secretase 1 A1A C00002477 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00009071 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00009071 3 / 3
P23467 Receptor-type tyrosine-protein phosphatase beta Receptor tyrosine-protein phosphatase C00009071 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00009071 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00002477 2 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00009071 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002477 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002477 0 / 0
O00167 Eyes absent homolog 2 Enzyme C00002477 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002477 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002477 1 / 0
Q05513 Protein kinase C zeta type Iota C00009071 0 / 0
Q04759 Protein kinase C theta type Delta C00009071 0 / 1
Q02156 Protein kinase C epsilon type Eta C00009071 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00009071 0 / 0
P17252 Protein kinase C alpha type Alpha C00009071 0 / 0
Q05655 Protein kinase C delta type Delta C00009071 0 / 0
P05129 Protein kinase C gamma type Alpha C00009071 1 / 1
P05771 Protein kinase C beta type Alpha C00009071 0 / 0
P24723 Protein kinase C eta type Eta C00009071 1 / 0
P41743 Protein kinase C iota type Iota C00009071 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00009071 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002477 1 / 1

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00002477

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#605361 Spinocerebellar ataxia 14; sca14 P05129
#601367 Stroke, ischemic P24723
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (13)

KEGG name UniProt
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00002477