Species

KNApSAcK Entry

Organism name Aloe castanea
Genus Aloe
Family Asphodelaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aloe castanea
Linked NCBI taxonomy ID 1128781
Linked level species

Family

Family in NCBI taxonomy Xanthorrhoeaceae
ID 27232

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00036708 External link 512 Aloin B
CHEMBL123026
CHEMBL497001
CHEMBL1569106
2 / 2 / 2 No. 826 No. 61
C00002797 External link 512 Aloin
/ Aloin A
/ Barbaloin
CHEMBL123026
CHEMBL497001
CHEMBL1569106
C045601
2 / 2 / 2 No. 826 No. 61
C00002415 External link 512 Aloesin
/ Aloe resin B
CHEMBL1343351
C069868
4 / 7 / 3 No. 1013 No. 15

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00002797 C00036708 1 / 1
Q9H244 P2Y purinoceptor 12 Purine receptor C00002797 C00036708 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00002415 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002415 7 / 3
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002415 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002415 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#609821 Bleeding disorder, platelet-type, 8; bdplt8 Q9H244
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (5)

KEGG name UniProt
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H01235 Bleeding disorder platelet-type Q9H244 (related)