Ammi visnaga
Species
KNApSAcK Entry
| Organism name | Ammi visnaga |
|---|---|
| Genus | Ammi |
| Family | Apiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Ammi visnaga |
|---|---|
| Linked NCBI taxonomy ID | 1053409 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Apiaceae |
|---|---|
| ID | 4037 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (15)
| Species | Activity |
|---|---|
| Ammi visnaga (L.) Lamarck | Antiatherosclerotic |
| Ammi visnaga (L.) Lamarck | Antipyretic |
| Ammi visnaga (L.) Lamarck | Antispasmodic |
| Ammi visnaga (L.) Lamarck | Calcium Antagonist |
| Ammi visnaga (L.) Lamarck | Cardiotonic |
| Ammi visnaga (L.) Lamarck | Coronary |
| Ammi visnaga (L.) Lamarck | Dilator |
| Ammi visnaga (L.) Lamarck | Diuretic |
| Ammi visnaga (L.) Lamarck | Hypoglycemic |
| Ammi visnaga (L.) Lamarck | Inotropic |
| Ammi visnaga (L.) Lamarck | Litholytic |
| Ammi visnaga (L.) Lamarck | Myocardiotonic |
| Ammi visnaga (L.) Lamarck | Myocontractant |
| Ammi visnaga (L.) Lamarck | phototoxic |
| Ammi visnaga (L.) Lamarck | Vasodilator |
Metabolite list (10)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004966
|
Rhamnetin 3-O-sulfate
|
No. 51 | No. 15 |
|
||||
|
C00004956
|
Quercetin 3-O-sulfate
|
CHEMBL1207957
|
No. 51 | No. 15 |
|
|||
|
C00004949
|
Rhamnocitrin 3-O-sulfate
|
No. 51 | No. 15 |
|
||||
|
C00002452
|
Athamantin
|
No. 224 | No. 25 |
|
||||
|
C00002468
|
Dihydrosamidin
|
CHEMBL1302867
|
13 / 28 / 22 | No. 224 | No. 25 |
|
||
|
C00002504
|
Visnadin
|
CHEMBL2104448
|
C067604
|
No. 224 | No. 25 |
|
||
|
C00002497
|
Samidin
|
No. 224 | No. 25 |
|
||||
|
C00002432
|
Khellol glucoside
|
CHEMBL2107506
|
C047312
|
No. 1253 | No. 15 |
|
||
|
C00002447
|
Visnagin
|
CHEMBL45176
|
C044999
|
6 / 6 / 5 | No. 4127 | No. 15 |
|
|
|
C00002431
|
Khellin
|
CHEMBL298070
|
D007666
|
0 / 1 | No. 5893 | No. 15 |
|
Human Protein / Gene in interactions
16 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002447 C00002468 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002447 C00002468 | 0 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002447 C00002468 | 2 / 2 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00002447 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00002447 | 3 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002468 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002468 | 2 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002468 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00002468 | 3 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002468 | 3 / 3 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002468 | 11 / 10 |
| P04062 | Glucosylceramidase | Enzyme | C00002468 | 6 / 4 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00002468 | 1 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002468 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002468 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002447 | 1 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (32)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG DISEASE (24)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|