PCIDB

Ptaeroxylon obliquum

Species

KNApSAcK Entry

Organism name Ptaeroxylon obliquum
Genus Ptaeroxylon
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ptaeroxylon obliquum
Linked NCBI taxonomy ID 77019
Linked level species

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00004564 External link 512 Ptaeroxylol
No. 3 No. 15
C00034885 External link 512 Prenyletin
CHEMBL607536
9 / 2 / 3 No. 466 No. 25
C00036121 External link 512 Heteropeucenin
No. 719
C00035893 External link 512 Umtatin
/ (-)-Umtatin
CHEMBL2087926
No. 719
C00002436 External link 512 5-O-Methylalloptaeroxylin
CHEMBL2164965
No. 1000 No. 15
C00002442 External link 512 Ptaeroglycol
No. 1000 No. 15
C00002441 External link 512 Perforamone D
/ Ptaerochromenol
CHEMBL2204370
No. 1000 No. 15
C00046214 External link 512 Obliquin
CHEMBL1525791
4 / 5 / 5 No. 2132

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
B2RXH2 Lysine-specific demethylase 4E Enzyme C00034885 C00046214 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00034885 C00046214 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00034885 C00046214 2 / 2
P55210 Caspase-7 C14 C00034885 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00034885 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00046214 3 / 3
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00034885 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00034885 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00034885 0 / 0
P29466 Caspase-1 C14 C00034885 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#119900 Digital clubbing, isolated congenital P15428
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)