Scaphopetalum thonneri

• Index
• Plant Species
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Scaphopetalum thonneri
Genus	Scaphopetalum
Family	Malvaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Scaphopetalum thonneri
Linked NCBI taxonomy ID	133581
Linked level	species

Family

Family in NCBI taxonomy	Malvaceae
ID	3629

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00019064	Oleanolic acid / Astrantiagenin C / Virgaureagenin B / 3beta-Hydroxyolean-12-en-28-oic acid	CHEMBL56615 CHEMBL168 CHEMBL180553 CHEMBL365375 CHEMBL486382 CHEMBL1413646 CHEMBL1436454	D009828	30 / 8 / 12	21 / 15	No. 13	No. 51
C00037794	Scaphopetalumate / (+)-Scaphopetalumate					No. 78
C00037793	Scaphopetalone					No. 406
C00002499	Scopoletin	CHEMBL71851	D012603	48 / 37 / 34	9 / 0	No. 864	No. 25

Human Protein / Gene in interactions

73 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002499 C00019064	0 / 0
P15121	Aldose reductase	Enzyme	C00002499 C00019064	0 / 0
O75496	Geminin	Unclassified protein	C00002499 C00019064	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002499 C00019064	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002499 C00019064	0 / 3
Q00796	Sorbitol dehydrogenase	Enzyme	C00002499	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00019064	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002499	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002499	0 / 0
P06746	DNA polymerase beta	Enzyme	C00019064	0 / 0
P04062	Glucosylceramidase	Enzyme	C00002499	6 / 4
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002499	1 / 1
P43166	Carbonic anhydrase 7	Lyase	C00002499	0 / 0
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00019064	4 / 2
P29466	Caspase-1	C14	C00002499	0 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002499	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002499	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002499	0 / 0
P24666	Low molecular weight phosphotyrosine protein phosphatase	Tyr	C00019064	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00019064	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00019064	0 / 0
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00002499	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002499	1 / 1
P00918	Carbonic anhydrase 2	Lyase	C00002499	1 / 2
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00019064	0 / 0
P10586	Receptor-type tyrosine-protein phosphatase F	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002499	0 / 1
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00019064	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002499	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002499	1 / 2
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002499	0 / 0
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00002499	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002499	1 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002499	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002499	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002499	3 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002499	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00019064	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002499	7 / 3
Q04206	Transcription factor p65	Transcription Factor	C00002499	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00019064	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00019064	2 / 2
P06280	Alpha-galactosidase A	Enzyme	C00002499	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00019064	0 / 0
P18433	Receptor-type tyrosine-protein phosphatase alpha	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00019064	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002499	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002499	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002499	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002499	2 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00019064	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002499	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002499	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00002499	1 / 0
Q99700	Ataxin-2	Unclassified protein	C00002499	1 / 1
P55210	Caspase-7	C14	C00002499	0 / 0
P35228	Nitric oxide synthase, inducible	Enzyme	C00019064	1 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002499	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002499	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00019064	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00019064	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002499	5 / 1
P17706	Tyrosine-protein phosphatase non-receptor type 2	Tyr	C00019064	0 / 1
P29350	Tyrosine-protein phosphatase non-receptor type 6	Tyr	C00019064	0 / 0
P04054	Phospholipase A2	Enzyme	C00019064	0 / 0
P23469	Receptor-type tyrosine-protein phosphatase epsilon	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002499	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002499	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002499	0 / 0
O00255	Menin	Unclassified protein	C00002499	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002499	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00019064	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00019064	1 / 4

30 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00019064
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00019064
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00019064
847	CAT	catalase (EC:1.11.1.6)	C00019064
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00019064
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00019064
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00019064
3065	HDAC1, GON-10, HD1, RPD3, RPD3L1	histone deacetylase 1 (EC:3.5.1.98)	C00019064
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00019064
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00019064
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00019064
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00019064
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00019064
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00019064
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00019064
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00019064
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00019064
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00019064
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00019064
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00019064
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00019064
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002499
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002499
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002499
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00002499
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002499
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002499
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002499
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002499
7508	XPC, RAD4, XP3, XPCC	xeroderma pigmentosum, complementation group C	C00002499

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions