| Organism name | Iris tenuifolia |
|---|---|
| Genus | Iris |
| Family | Iridaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Iris tenuifolia |
|---|---|
| Linked NCBI taxonomy ID | 198827 |
| Linked level | species |
| Family in NCBI taxonomy | Iridaceae |
|---|---|
| ID | 26339 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00033051
|
Irisoid A
|
No. 3 | No. 15 |
|
||||
|
C00009825
|
5,7-Dihydroxy-2',6-dimethoxyisoflavone
/ 5,7-Dihydroxy-6,2'-dimethoxyisoflavone |
CHEMBL479118
|
No. 3 | No. 15 |
|
|||
|
C00004536
|
Izalpinin
/ 7-O-Methylgalangin / Galangin 7-methyl ether / 3,5-Dihydroxy-7-methoxyflavone / 3,5-Dihydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one |
CHEMBL464966
|
No. 3 | No. 15 |
|
|||
|
C00014131
|
5,2',3'-Trihydroxy-6,7-methylenedioxyflavanone
|
CHEMBL1807889
|
No. 25 | No. 14 |
|
|||
|
C00014118
|
5,2',3'-Trihydroxy-7-methoxyflavanone
|
No. 25 | No. 14 |
|
||||
|
C00014125
|
5,3'-Dihydroxy-7,2'-dimethoxyflavanone
|
No. 25 | No. 14 |
|
||||
|
C00014115
|
5,2'-Dihydroxy-6,7-methylenedioxyflavanone
|
No. 25 | No. 14 |
|
||||
|
C00002509
|
Betavulgarin
/ 2'-Hydroxy-5-methoxy-6,7-methylenedioxyisoflavone |
No. 27 | No. 15 |
|
||||
|
C00009857
|
Irisone A
/ 5-Hydroxy-2'-methoxy-6,7-methylenedioxyisoflavone |
CHEMBL509631
|
C053587
|
No. 27 | No. 15 |
|
||
|
C00009856
|
Irisone B
/ 5,2'-Dihydroxy-6,7-methylenedioxyisoflavone |
CHEMBL443974
|
C053588
|
No. 27 | No. 15 |
|
||
|
C00034310
|
Tenuifone
|
No. 27 | No. 15 |
|
||||
|
C00014366
|
3,5,2',3'-Tetrahydroxy-7-methoxyflavanone
|
No. 42 | No. 14 |
|
||||
|
C00008549
|
Alpinone
|
CHEMBL1081328
|
No. 42 | No. 14 |
|
|||
|
C00014367
|
3,5,3'-Trihydroxy-7,2'-dimethoxyflavanone
|
No. 42 | No. 14 |
|
||||
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00033651
|
Arborinone
|
No. 198 | No. 52 |
|
||||
|
C00034309
|
Tenuifodione
|
No. 5627 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003672 | 1 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00003672 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00003672 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 |
| P08183 | Multidrug resistance protein 1 | drug | C00003672 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003672 | 0 / 1 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 |
| P14679 | Tyrosinase | Oxidoreductase | C00003672 | 4 / 2 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003672 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00003672 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003672 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003672 | 0 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|