PCIDB

Vanilla spp.

Family in NCBI taxonomy	Orchidaceae
ID	4747

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	Liliopsida
ID	4447

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00002636	Anisaldehyde / p-Anisaldehyde	CHEMBL161598	C024896	11 / 18 / 13	1 / 0	No. 1003
C00002666	Piperonal	CHEMBL271663	C005454	3 / 4 / 4		No. 4093

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P00352	Retinal dehydrogenase 1	Enzyme	C00002636 C00002666	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002636	5 / 3
P10828	Thyroid hormone receptor beta	NR1A2	C00002636	3 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00002636	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002636	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00002636	4 / 2
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00002636	1 / 1
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00002636	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002636	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002666	3 / 3
P03372	Estrogen receptor	NR3A1	C00002636	1 / 1
P10275	Androgen receptor	NR3C4	C00002636	3 / 4
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002666	1 / 1

gene	gene name	gene description	KNApSAcK metabolite in interactions
8989	TRPA1, ANKTM1, FEPS	transient receptor potential cation channel, subfamily A, member 1	C00002636

OMIM	preferred title	UniProt
#300438	17-beta-hydroxysteroid dehydrogenase x deficiency	Q99714
#103470	Albinism, ocular, with sensorineural deafness	P14679
#203100	Albinism, oculocutaneous, type ia; oca1a	P14679
#606952	Albinism, oculocutaneous, type ib; oca1b	P14679
#300068	Androgen insensitivity syndrome; ais	P10275
#312300	Androgen insensitivity, partial; pais	P10275
%606641	Body mass index; bmi	P37231
#609338	Carotid intimal medial thickness 1	P37231
#615363	Estrogen resistance; estrr	P03372
#613163	Gaba-transaminase deficiency	P80404
#137800	Glioma susceptibility 1; glm1	P37231
#604367	Lipodystrophy, familial partial, type 3; fpld3	P37231
#300705	Mental retardation, x-linked 17; mrx17	Q99714
#300220	Mental retardation, x-linked, syndromic 10; mrxs10	Q99714
#601665	Obesity	P37231
#601800	Skin/hair/eye pigmentation, variation in, 3; shep3	P14679
#313200	Spinal and bulbar muscular atrophy, x-linked 1; smax1	P10275
#607250	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1	Q9NUW8
#271980	Succinic semialdehyde dehydrogenase deficiency; ssadhd	P51649
#188570	Thyroid hormone resistance, generalized, autosomal dominant; grth	P10828
#274300	Thyroid hormone resistance, generalized, autosomal recessive; grth	P10828
#145650	Thyroid hormone resistance, selective pituitary; prth	P10828

KEGG	name	UniProt
H00026	Endometrial Cancer	P03372 (marker)
H00024	Prostate cancer	P10275 (related)
H00062	Spinal and bulbar muscular atrophy (SBMA)	P10275 (related)
H00608	46,XY disorders of sex development (Disorders in androgen synthesis or action)	P10275 (related)
H00609	46,XY disorders of sex development (Other)	P10275 (related)
H00249	Thyroid hormone resistance syndrome	P10828 (related)
H00168	Oculocutaneous albinism (OCA)	P14679 (related)
H00038	Malignant melanoma	P14679 (marker)
H00032	Thyroid cancer	P37231 (related)
H00409	Type II diabetes mellitus	P37231 (related)
H00420	Familial partial lipodystrophy (FPL)	P37231 (related)
H00835	Succinic semialdehyde dehydrogenase (SSADH) deficiency	P51649 (related)
H01257	GABA-transaminase deficiency	P80404 (related)
H00480	Non-syndromic X-linked mental retardation	Q99714 (related)
H00658	Syndromic X-linked mental retardation	Q99714 (related)
H00925	2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency	Q99714 (related)
H00063	Spinocerebellar ataxia (SCA)	Q9NUW8 (related)