PCIDB

KNApSAcK Metabolite C00002636

Metabolite

KNApSAcK Entry

id C00002636
Name Anisaldehyde / p-Anisaldehyde
CAS RN 123-11-5
Standard InChI InChI=1S/C8H8O2/c1-10-8-4-2-7(6-9)3-5-8/h2-6H,1H3
Standard InChI (Main Layer) InChI=1S/C8H8O2/c1-10-8-4-2-7(6-9)3-5-8/h2-6H,1H3

Cluster

Phytochemical cluster
KCF-S cluster No. 1003

Link

ChEMBL

By standard InChI CHEMBL161598
By standard InChI Main Layer CHEMBL161598

KEGG

By LinkDB C10761

CTD

By CAS RN C024896

Human Protein / Gene in interaction

11 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL161598 CHEMBL1794561 (1)
3 / 1
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase CHEMBL161598 CHEMBL867028 (1)
1 / 1
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL161598 CHEMBL1614458 (1)
0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 CHEMBL161598 CHEMBL832816 (1)
0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL161598 CHEMBL1794401 (1)
0 / 0
P14679 Tyrosinase Oxidoreductase CHEMBL161598 CHEMBL813550 (1)
4 / 2
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL161598 CHEMBL1794510 (1)
5 / 3
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase CHEMBL161598 CHEMBL867027 (1)
1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL161598 CHEMBL830921 (1)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL161598 CHEMBL1941568 (1) CHEMBL1941569 (1)
1 / 1
P10275 Androgen receptor NR3C4 CHEMBL161598 CHEMBL1794560 (1)
3 / 4

CTD interaction (1)

compound gene gene name gene description interaction interaction type form reference
pmid
C024896 8989 TRPA1
ANKTM1
FEPS
transient receptor potential cation channel, subfamily A, member 1 4-anisaldehyde results in increased activity of TRPA1 protein increases activity
protein 21591660

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#615363 Estrogen resistance; estrr P03372
#613163 Gaba-transaminase deficiency P80404
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (13)

KEGG disease name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H01257 GABA-transaminase deficiency P80404 (related)