PCIDB

Illicium verum

Species

KNApSAcK Entry

Organism name Illicium verum
Genus Illicium
Family Illiciaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Illicium verum
Linked NCBI taxonomy ID 124778
Linked level species

Family

Family in NCBI taxonomy Schisandraceae
ID 16733

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Natural Activity

List (62)

Species Activity
Illicium verum Hook. F. Allergenic
Illicium verum Hook. F. Analgesic
Illicium verum Hook. F. Anemia
Illicium verum Hook. F. Anorexia
Illicium verum Hook. F. Antibacterial
Illicium verum Hook. F. Antiseptic
Illicium verum Hook. F. Antispasmodic
Illicium verum Hook. F. Arthrosis
Illicium verum Hook. F. Bacteria
Illicium verum Hook. F. Bronchosecretolytic
Illicium verum Hook. F. Bronchosis
Illicium verum Hook. F. Candida
Illicium verum Hook. F. Carminative
Illicium verum Hook. F. Catarrh
Illicium verum Hook. F. Cholecytosis
Illicium verum Hook. F. Colic
Illicium verum Hook. F. Congestion
Illicium verum Hook. F. Constipation
Illicium verum Hook. F. Cough
Illicium verum Hook. F. Cramp
Illicium verum Hook. F. Digestive
Illicium verum Hook. F. Diuretic
Illicium verum Hook. F. Dysentery
Illicium verum Hook. F. Dyspepsia
Illicium verum Hook. F. Enterosis
Illicium verum Hook. F. Estrogenic
Illicium verum Hook. F. Expectorant
Illicium verum Hook. F. Extrophy
Illicium verum Hook. F. Favus
Illicium verum Hook. F. Frigidity
Illicium verum Hook. F. Fungicide
Illicium verum Hook. F. Fungus
Illicium verum Hook. F. Gas
Illicium verum Hook. F. Gastrosis
Illicium verum Hook. F. Halitosis
Illicium verum Hook. F. Hemopareisis
Illicium verum Hook. F. Hernia
Illicium verum Hook. F. Infection
Illicium verum Hook. F. Inflammation
Illicium verum Hook. F. Insecticide
Illicium verum Hook. F. Insomnia
Illicium verum Hook. F. Lactagogue
Illicium verum Hook. F. Lumbago
Illicium verum Hook. F. Morning Sickness
Illicium verum Hook. F. Mutagenic
Illicium verum Hook. F. Mycosis
Illicium verum Hook. F. Nausea
Illicium verum Hook. F. Nervousness
Illicium verum Hook. F. Otosis
Illicium verum Hook. F. Pain
Illicium verum Hook. F. Paralysis
Illicium verum Hook. F. Parturition
Illicium verum Hook. F. Pediculicide
Illicium verum Hook. F. Piscicide
Illicium verum Hook. F. Respirosis
Illicium verum Hook. F. Rheumatism
Illicium verum Hook. F. Scabies
Illicium verum Hook. F. Spasm
Illicium verum Hook. F. Stimulant
Illicium verum Hook. F. Stomach Distress
Illicium verum Hook. F. Stomachic
Illicium verum Hook. F. Toothache

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002636 External link 512 Anisaldehyde
/ p-Anisaldehyde
CHEMBL161598
C024896
11 / 18 / 13 1 / 0 No. 1003
C00002757 External link 512 4-Methoxycinnamaldehyde
/ p-Methoxycinnamaldehyde
CHEMBL452173
No. 2748 No. 6

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10828 Thyroid hormone receptor beta NR1A2 C00002636 3 / 1
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00002636 1 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002636 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00002636 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002636 0 / 0
P14679 Tyrosinase Oxidoreductase C00002636 4 / 2
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00002636 5 / 3
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00002636 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002636 0 / 0
P03372 Estrogen receptor NR3A1 C00002636 1 / 1
P10275 Androgen receptor NR3C4 C00002636 3 / 4

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
8989 TRPA1, ANKTM1, FEPS transient receptor potential cation channel, subfamily A, member 1 C00002636

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#615363 Estrogen resistance; estrr P03372
#613163 Gaba-transaminase deficiency P80404
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (13)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H01257 GABA-transaminase deficiency P80404 (related)