PCIDB

Beilschmiedia erythrophloia

Species

KNApSAcK Entry

Organism name Beilschmiedia erythrophloia
Genus Beilschmiedia
Family Lauraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Beilschmiedia
Linked NCBI taxonomy ID 88849
Linked level genus

Family

Family in NCBI taxonomy Lauraceae
ID 3433

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (17)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00047146 External link 512 3-O-Acetyl-epi-betulinic acid
CHEMBL312687
CHEMBL182981
2 / 0 / 0 No. 23 No. 51
C00003749 External link 512 Lupeol
/ Lupenol
/ (+)-Lupenol
CHEMBL289191
CHEMBL459702
C010480
3 / 0 / 0 2 / 6 No. 23 No. 51
C00047141 External link 512 24(S)-3beta-Hydroxystigmast-5-en-7-one
CHEMBL254780
CHEMBL483850
No. 53 No. 11
C00047355 External link 512 Suberosol B
/ (-)-Suberosol B
CHEMBL509590
CHEMBL463055
No. 500
C00030755 External link 512 Methyl palmitate
/ Methyl hexadecanoate
CHEMBL335125
C019012
2 / 0 / 0 0 / 1 No. 793
C00002683 External link 512 Vanillin
CHEMBL13883
18 / 8 / 9 No. 1003
C00030760 External link 512 Methyl oleate
/ Oleic acid methyl ester
/ Methyl (Z)-9-octadecenoate
CHEMBL465725
C005576
2 / 6 / 5 No. 1785
C00030757 External link 512 Methyl linoleate
/ Methyl 9Z,12Z-octadecadienoate
C005575
No. 1785
C00028200 External link 512 Dioxamine
No. 2200
C00047164 External link 512 alpha-Tocopherylquinone
CHEMBL1223852
CHEMBL1254448
C002421
5 / 2 / 3 No. 3729
C00047225 External link 512 Erythrophloin B
No. 4123
C00047228 External link 512 Erythrophloin E
No. 4123
C00047227 External link 512 Erythrophloin D
No. 4123
C00047226 External link 512 Erythrophloin C
CHEMBL559652
No. 4304
C00047224 External link 512 Erythrophloin A
No. 4304
C00047229 External link 512 Erythrophloin F
No. 4304
C00047190 External link 512 Beilcyclone A
No. 8284

Human Protein / Gene in interactions

31 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10275 Androgen receptor NR3C4 C00002683 C00030760 3 / 4
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002683 0 / 0
P78527 DNA-dependent protein kinase catalytic subunit Atypical serine/threonine protein kinase PIKK subfamily C00002683 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003749 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00030760 3 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00002683 0 / 0
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00002683 1 / 1
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002683 0 / 0
Q02156 Protein kinase C epsilon type Eta C00047146 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00047164 0 / 1
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00002683 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00003749 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00003749 0 / 0
P34972 Cannabinoid receptor 2 Cannabinoid receptor C00030755 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002683 0 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00002683 0 / 0
O00519 Fatty-acid amide hydrolase 1 Enzyme C00002683 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00030755 0 / 0
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00002683 1 / 1
Q96RI1 Bile acid receptor NR1H4 C00002683 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00047164 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002683 2 / 2
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00002683 0 / 0
P05771 Protein kinase C beta type Alpha C00047146 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00047164 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00047164 0 / 1
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002683 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002683 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00047164 1 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002683 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002683 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00003749
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) C00003749

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#613163 Gaba-transaminase deficiency P80404
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (13)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

7 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006528 Carcinoma, Hepatocellular C00003749
D009202 Cardiomyopathies C00003749
D006937 Hypercholesterolemia C00003749
D009374 Neoplasms, Experimental C00003749
D012878 Skin Neoplasms C00003749
D014947 Wounds and Injuries C00003749
D011658 Pulmonary Fibrosis C00030755