Picrorhiza kurroa

• Index
• Plant Species
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Picrorhiza kurroa
Genus	Picrorhiza
Family	Plantaginaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Picrorhiza kurrooa
Linked NCBI taxonomy ID	195120
Linked level	species

Family

Family in NCBI taxonomy	Plantaginaceae
ID	156152

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00031028	Picroside I	CHEMBL454577	C109270			No. 120	No. 36
C00010514	Picroside II / Vanilloyl catalpol	CHEMBL510404	C416837	1 / 0 / 0	0 / 1	No. 287	No. 36
C00031030	Pikuroside / (-)-Pikuroside					No. 287	No. 36
C00002689	Apocynin / Acetovanillone	CHEMBL346919	C056165	2 / 0 / 0	43 / 10	No. 1494

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00002689	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002689	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00010514	0 / 0

43 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
183	AGT, ANHU, SERPINA8	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	C00002689
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00002689
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002689
6356	CCL11, SCYA11	chemokine (C-C motif) ligand 11	C00002689
6362	CCL18, AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	C00002689
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002689
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00002689
6354	CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7	chemokine (C-C motif) ligand 7	C00002689
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00002689
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00002689
2919	CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	C00002689
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00002689
1536	CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX	cytochrome b-245, beta polypeptide	C00002689
2033	EP300, KAT3B, RSTS2, p300	E1A binding protein p300 (EC:2.3.1.48)	C00002689
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00002689
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00002689
27429	HTRA2, OMI, PARK13, PRSS25	HtrA serine peptidase 2 (EC:3.4.21.108)	C00002689
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002689
3456	IFNB1, IFB, IFF, IFNB	interferon, beta 1, fibroblast	C00002689
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002689
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002689
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002689
3684	ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6	integrin, alpha M (complement component 3 receptor 3 subunit)	C00002689
3717	JAK2, JTK10, THCYT3	Janus kinase 2 (EC:2.7.10.2)	C00002689
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00002689
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002689
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002689
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002689
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00002689
4282	MIF, GIF, GLIF, MMIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1)	C00002689
4322	MMP13, CLG3, MANDP1	matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-)	C00002689
4481	MSR1, CD204, SCARA1, SR-A, SRA, phSR1, phSR2	macrophage scavenger receptor 1	C00002689
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00002689
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00002689
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00002689
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00002689
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002689
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002689
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00002689
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00002689
7082	TJP1, ZO-1	tight junction protein 1	C00002689
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002689
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002689

Related Diseases

Diseases related to CTD interactions