Species

KNApSAcK Entry

Organism name Cynanchum paniculatum
Genus Cynanchum
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Vincetoxicum pycnostelma
Linked NCBI taxonomy ID 228726
Linked level species

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002704 External link 512 Paeonol
CHEMBL1079227
C013638
4 / 2 / 3 No. 1494
C00043761 External link 512 Neocynapanogenin C
No. 1793
C00043760 External link 512 Neocynapanogenin B
No. 1793
C00043801 External link 512 Paniculatumoside A
/ (-)-Paniculatumoside A
No. 1793
C00043802 External link 512 Paniculatumoside B
/ (+)-Paniculatumoside B
No. 1793

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00352 Retinal dehydrogenase 1 Enzyme C00002704 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002704 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002704 2 / 2
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002704 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#119900 Digital clubbing, isolated congenital P15428
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)