Rehmannia glutinosa
Species
KNApSAcK Entry
| Organism name | Rehmannia glutinosa |
|---|---|
| Genus | Rehmannia |
| Family | Scrophulariaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Rehmannia glutinosa |
|---|---|
| Linked NCBI taxonomy ID | 99300 |
| Linked level | species |
Family
| Family in NCBI taxonomy | |
|---|---|
| ID |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (41)
| Species | Activity |
|---|---|
| Rehmannia glutinosa (Gaertn.) Steud. | Adrenal Stimulant |
| Rehmannia glutinosa (Gaertn.) Steud. | Aldose-Reductase Inhibitor |
| Rehmannia glutinosa (Gaertn.) Steud. | Antiaging |
| Rehmannia glutinosa (Gaertn.) Steud. | Antiallergic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antiarthritic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antiasthmatic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antibacterial |
| Rehmannia glutinosa (Gaertn.) Steud. | Antidiabetic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antihemorrhagic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antihepatomic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antiinflammatory |
| Rehmannia glutinosa (Gaertn.) Steud. | Antipyretic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antisarcomic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antiseptic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antithrombic |
| Rehmannia glutinosa (Gaertn.) Steud. | Antithromboxane |
| Rehmannia glutinosa (Gaertn.) Steud. | Antitumor |
| Rehmannia glutinosa (Gaertn.) Steud. | Bitter |
| Rehmannia glutinosa (Gaertn.) Steud. | Cardiodepressant |
| Rehmannia glutinosa (Gaertn.) Steud. | Cardiotonic |
| Rehmannia glutinosa (Gaertn.) Steud. | Cyclooxygenase Inhibitor |
| Rehmannia glutinosa (Gaertn.) Steud. | Diuretic |
| Rehmannia glutinosa (Gaertn.) Steud. | Fungicide |
| Rehmannia glutinosa (Gaertn.) Steud. | Hemopoietic |
| Rehmannia glutinosa (Gaertn.) Steud. | Hemostat |
| Rehmannia glutinosa (Gaertn.) Steud. | Hepatoprotective |
| Rehmannia glutinosa (Gaertn.) Steud. | Hypertensive |
| Rehmannia glutinosa (Gaertn.) Steud. | Hypoglycemic |
| Rehmannia glutinosa (Gaertn.) Steud. | Hypotensive |
| Rehmannia glutinosa (Gaertn.) Steud. | Immunodepressant |
| Rehmannia glutinosa (Gaertn.) Steud. | Immunomodulator |
| Rehmannia glutinosa (Gaertn.) Steud. | Immunostimulant |
| Rehmannia glutinosa (Gaertn.) Steud. | Laxative |
| Rehmannia glutinosa (Gaertn.) Steud. | Lioxygenase Inhibitor |
| Rehmannia glutinosa (Gaertn.) Steud. | Mutagenic |
| Rehmannia glutinosa (Gaertn.) Steud. | Nephroprotective |
| Rehmannia glutinosa (Gaertn.) Steud. | Phagocytotic |
| Rehmannia glutinosa (Gaertn.) Steud. | Sialagogue |
| Rehmannia glutinosa (Gaertn.) Steud. | Tranquilizer |
| Rehmannia glutinosa (Gaertn.) Steud. | Vasoconstrictor |
| Rehmannia glutinosa (Gaertn.) Steud. | Vasodilator |
Metabolite list (20)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002744
|
Forsythiaside
/ Forsythoside A |
CHEMBL504363
|
C058049
|
1 / 0 / 0 | No. 33 |
|
||
|
C00002754
|
Jionoside B1
|
CHEMBL233094
|
No. 33 |
|
||||
|
C00002767
|
Plantamajoside
|
C421173
|
No. 33 |
|
||||
|
C00002769
|
Purpureaside C
|
CHEMBL393090
CHEMBL510539 |
6 / 3 / 4 | No. 33 |
|
|||
|
C00003075
|
Catalpol
|
CHEMBL513223
|
C078040
|
2 / 1 / 1 | 0 / 2 | No. 64 | No. 36 |
|
|
C00010519
|
Rehmannioside B
|
No. 222 |
|
|||||
|
C00033579
|
6-Feruloyl ajugol
/ 6-O-(E)-Feruloyl ajugol |
No. 287 | No. 36 |
|
||||
|
C00010995
|
Rehmapicroside
|
No. 316 |
|
|||||
|
C00010674
|
Jioglutin A
|
No. 787 |
|
|||||
|
C00010675
|
Jioglutin B
|
No. 787 |
|
|||||
|
C00010672
|
Rehmaglutin D
|
No. 787 |
|
|||||
|
C00010670
|
Rehmaglutin A
|
CHEMBL2332356
|
1 / 0 / 0 | No. 787 |
|
|||
|
C00010671
|
Jioglutin C
|
No. 787 |
|
|||||
|
C00010673
|
Rehmaglutin B
|
No. 787 |
|
|||||
|
C00010626
|
Rehmannioside D
|
No. 1212 |
|
|||||
|
C00010585
|
Jioglutolide
|
No. 2521 |
|
|||||
|
C00010584
|
Jioglutin E
|
No. 2609 |
|
|||||
|
C00010568
|
Glutinoside
|
No. 3854 |
|
|||||
|
C00010676
|
Rehmaglutin C
|
No. 6059 |
|
|||||
|
C00010583
|
Jiofuran
|
No. 6735 |
|
Human Protein / Gene in interactions
10 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P17252 | Protein kinase C alpha type | Alpha | C00002744 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002769 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003075 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00002769 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002769 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002769 | 3 / 3 |
| P03372 | Estrogen receptor | NR3A1 | C00003075 | 1 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002769 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002769 | 0 / 1 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00010670 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (4)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
KEGG DISEASE (5)
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|