Species

KNApSAcK Entry

Organism name Clinopodium chinense var. parviflorum
Genus Clinopodium
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Clinopodium chinense var. parviflorum
Linked NCBI taxonomy ID 758499
Linked level varietas

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00047811 External link 512 Clinopodic acid D
/ (-)-Clinopodic acid D
CHEMBL1079356
No. 494
C00047814 External link 512 Clinopodic acid H
/ (+)-Clinopodic acid H
No. 494
C00047813 External link 512 Clinopodic acid G
/ (+)-Clinopodic acid G
No. 494
C00047810 External link 512 Clinopodic acid C
/ (-)-Clinopodic acid C
CHEMBL1080779
CHEMBL1081512
No. 494
C00047812 External link 512 Clinopodic acid F
/ (+)-Clinopodic acid F
CHEMBL1079356
No. 494
C00002770 External link 512 Rosmarinic acid
CHEMBL66966
CHEMBL324842
CHEMBL1315100
CHEMBL2111558
48 / 35 / 38 No. 749
C00047809 External link 512 Clinopodic acid B
/ (+)-Clinopodic acid B
CHEMBL1080778
No. 749
C00047808 External link 512 Clinopodic acid A
/ (+)-Clinopodic acid A
CHEMBL1079231
No. 749
C00047815 External link 512 Clinopodic acid I
No. 1276

Human Protein / Gene in interactions

48 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002770 1 / 0
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00002770 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00002770 0 / 0
P14618 Pyruvate kinase PKM Enzyme C00002770 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002770 0 / 3
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002770 3 / 0
P06746 DNA polymerase beta Enzyme C00002770 0 / 0
P04062 Glucosylceramidase Enzyme C00002770 6 / 4
P10253 Lysosomal alpha-glucosidase Hydrolase C00002770 1 / 1
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00002770 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00002770 3 / 1
P06241 Tyrosine-protein kinase Fyn Src C00002770 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002770 0 / 1
P54132 Bloom syndrome protein Enzyme C00002770 1 / 2
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00002770 1 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002770 0 / 0
P39748 Flap endonuclease 1 Enzyme C00002770 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002770 0 / 0
P15121 Aldose reductase Enzyme C00002770 0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00002770 1 / 2
P03956 Interstitial collagenase M10A C00002770 0 / 1
Q9Y253 DNA polymerase eta Enzyme C00002770 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00002770 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002770 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00002770 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002770 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002770 3 / 3
P51692 Signal transducer and activator of transcription 5B Unclassified protein C00002770 1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002770 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002770 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002770 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002770 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00002770 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002770 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002770 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002770 4 / 3
P06239 Tyrosine-protein kinase Lck Src C00002770 0 / 1
Q12794 Hyaluronidase-1 Enzyme C00002770 1 / 2
Q9UBT6 DNA polymerase kappa Enzyme C00002770 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002770 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00002770 0 / 0
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein C00002770 3 / 3
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002770 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002770 1 / 1
Q13951 Core-binding factor subunit beta Unclassified protein C00002770 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00002770 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002770 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00002770 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (35)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#600807 Asthma, susceptibility to Q13093
#209950 Atypical mycobacteriosis, familial P42224
#210900 Bloom syndrome; blm P54132
#614162 Candidiasis, familial, 7; candf7 P42224
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#245590 Growth hormone insensitivity with immunodeficiency P51692
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#147050 Ige responsiveness, atopic; iger Q13093
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#601492 Mucopolysaccharidosis, type ix; mps9 Q12794
#613796 Mycobacterial and viral infections, susceptibility to, autosomal recessive P42224
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (38)

KEGG name UniProt
H00028 Choriocarcinoma P03956 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00089 IFN-gamma/IL-12 axis P42224 (related)
H00363 Candidiasis P42224 (related)
H01109 Chronic mucocutaneous candidiasis (CMC) P42224 (related)
H00931 Growth hormone insensitivity with immunodeficiency P51692 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00133 Mucopolysaccharidosis type IX (MPS9) Q12794 (related)
H00421 Mucopolysaccharidosis (MPS) Q12794 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)