Rhamnus cathartica

• Index
• Plant Species
• Natural Activity
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Rhamnus cathartica
Genus	Rhamnus
Family	Rhamnaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Rhamnus cathartica
Linked NCBI taxonomy ID	3610
Linked level	species

Family

Family in NCBI taxonomy	Rhamnaceae
ID	3608

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Natural Activity

List (7)

Species	Activity
Rhamnus cathartica L.	Antitumor
Rhamnus cathartica L.	Collyrium
Rhamnus cathartica L.	Depurative
Rhamnus cathartica L.	Diuretic
Rhamnus cathartica L.	Emetic
Rhamnus cathartica L.	Laxative
Rhamnus cathartica L.	Peristaltic

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00004634	Rhamnetin / 7-Methoxyquercetin / 3,5,3',4'-Tetrahydroxy-7-methoxyflavone / 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1- benzopyran-4-one	CHEMBL312163	C063423	20 / 27 / 27		No. 3	No. 15
C00004642	Rhamnazin / 7,3'-Di-O-methylquercetin / 3,4',5-Trihydroxy-3',7-dimethoxyflavone / 3,5-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one	CHEMBL457148				No. 3	No. 15
C00004567	Rhamnocitrin / 7-Methylkaempferol / 3,4',5-Trihydroxy-7-methoxyflavone / 3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one	CHEMBL442289				No. 3	No. 15
C00005518	Rhamnetin 3-rhamninoside / Rhamnetin 3-O-rhamninoside	CHEMBL500372				No. 5	No. 15
C00002825	Frangulin B	CHEMBL496999	C007781	2 / 1 / 1		No. 568	No. 62
C00002824	Frangulin A	CHEMBL1172006		1 / 1 / 1		No. 568	No. 62

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9H244	P2Y purinoceptor 12	Purine receptor	C00002824 C00002825	1 / 1
P45983	Mitogen-activated protein kinase 8	Jnk	C00004634	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00004634	11 / 10
P10828	Thyroid hormone receptor beta	NR1A2	C00004634	3 / 1
P04792	Heat shock protein beta-1	Unclassified protein	C00004634	2 / 1
P11388	DNA topoisomerase 2-alpha	Isomerase	C00002825	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00004634	0 / 0
P15121	Aldose reductase	Enzyme	C00004634	0 / 0
P45984	Mitogen-activated protein kinase 9	Jnk	C00004634	0 / 0
P04745	Alpha-amylase 1	Enzyme	C00004634	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00004634	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00004634	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00004634	3 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00004634	0 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00004634	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00004634	4 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00004634	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00004634	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00004634	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00004634	1 / 1
O00255	Menin	Unclassified protein	C00004634	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00004634	1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions