Species

KNApSAcK Entry

Organism name Diphysa robinoides
Genus Diphysa
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Diphysa
Linked NCBI taxonomy ID 48132
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009957 External link 512 Diphysolone
/ 5,7,2',4'-Tetrahydroxy-6-prenylisoflavanone
No. 28 No. 14
C00009958 External link 512 Diphysolidone
/ 5,7,2'-Trihydroxy-4'-methoxy-6-prenylisoflavanone
No. 28 No. 14
C00010035 External link 512 4'-O-Methylpreglabridin
/ (3S)-7,2'-Dihydroxy-4'-methoxy-8-prenylisoflavan
CHEMBL503741
No. 296 No. 14
C00006584 External link 512 Diphysin
No. 3173
C00002835 External link 512 Lapachol
CHEMBL15193
C008252
13 / 20 / 50 No. 4183 No. 80

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor C00002835 7 / 37
Q16637 Survival motor neuron protein Unclassified protein C00002835 4 / 1
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00002835 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00002835 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00002835 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002835 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002835 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002835 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002835 4 / 3
Q04760 Lactoylglutathione lyase Enzyme C00002835 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002835 0 / 0
O00255 Menin Unclassified protein C00002835 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002835 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (20)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#133239 Esophageal cancer P04637
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (50)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)