Genipa americana L.
Species
KNApSAcK Entry
| Organism name | Genipa americana L. |
|---|---|
| Genus | Genipa |
| Family | Rubiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Genipa |
|---|---|
| Linked NCBI taxonomy ID | 58485 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Rubiaceae |
|---|---|
| ID | 24966 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (50)
| Species | Activity |
|---|---|
| Genipa americana L. | A-beta-Blocker |
| Genipa americana L. | Abortifacient |
| Genipa americana L. | Algacide |
| Genipa americana L. | Anti-TNF-alpha |
| Genipa americana L. | Anti-Tumor-Promoter |
| Genipa americana L. | Antiabortive |
| Genipa americana L. | Antiaggregant |
| Genipa americana L. | Antialzheimeran |
| Genipa americana L. | Antiangiogenic |
| Genipa americana L. | Antiarthritic |
| Genipa americana L. | Anticlastogenic |
| Genipa americana L. | Antiedemic |
| Genipa americana L. | Antihepatomic |
| Genipa americana L. | Antiinflammatory |
| Genipa americana L. | Antimutagenic |
| Genipa americana L. | Antioxidant |
| Genipa americana L. | Antiplatelet |
| Genipa americana L. | Antiscorbutic |
| Genipa americana L. | Antiseptic |
| Genipa americana L. | Antithrombic |
| Genipa americana L. | Anxiolytic |
| Genipa americana L. | Aphrodisiac |
| Genipa americana L. | Apoptotic |
| Genipa americana L. | Astringent |
| Genipa americana L. | Bactericide |
| Genipa americana L. | Cholagogue |
| Genipa americana L. | Choleretic |
| Genipa americana L. | Cicatrizant |
| Genipa americana L. | Collagenic |
| Genipa americana L. | Collyrium |
| Genipa americana L. | Contraceptive |
| Genipa americana L. | Depurative |
| Genipa americana L. | Digestive |
| Genipa americana L. | Diuretic |
| Genipa americana L. | Emetic |
| Genipa americana L. | Febrifuge |
| Genipa americana L. | Fungicide |
| Genipa americana L. | Glutathionigenic |
| Genipa americana L. | Hepatoprotective |
| Genipa americana L. | IL2-Inhibitor |
| Genipa americana L. | Immunosuppressive |
| Genipa americana L. | Insectifuge |
| Genipa americana L. | Neuritogenic |
| Genipa americana L. | Neuroprotective |
| Genipa americana L. | Orexigenic |
| Genipa americana L. | Protisticide |
| Genipa americana L. | Purgative |
| Genipa americana L. | Stomachic |
| Genipa americana L. | Tonic |
| Genipa americana L. | Vulnerary |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00031810
|
Genameside B
|
No. 56 | No. 36 |
|
||||
|
C00003081
|
Gardenoside
|
CHEMBL485798
CHEMBL1079679 CHEMBL1482711 CHEMBL2133850 |
C056587
|
14 / 2 / 5 | No. 56 | No. 36 |
|
|
|
C00031809
|
Genameside A
/ (-)-Genameside A |
No. 56 | No. 36 |
|
||||
|
C00000320
|
Geniposide
|
CHEMBL462894
CHEMBL1417490 CHEMBL1718933 |
C007835
|
3 / 2 / 3 | 3 / 0 | No. 100 | No. 36 |
|
|
C00031811
|
Genameside C
/ (-)-Genameside C |
No. 222 |
|
|||||
|
C00031812
|
Genameside D
/ (+)-Genameside D |
No. 222 |
|
Human Protein / Gene in interactions
16 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00000320 C00003081 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000320 | 0 / 0 |
| Q9GZU7 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 | Enzyme | C00003081 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000320 | 2 / 3 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003081 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00003081 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00003081 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003081 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00003081 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00003081 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00003081 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00003081 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00003081 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00003081 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00003081 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00003081 | 0 / 0 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00000320
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000320
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000320
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (4)
| OMIM | preferred title | UniProt |
|---|---|---|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|